HCSGD entry for CACNB1

1. General information

Official gene symbolCACNB1
Entrez ID782
Gene full namecalcium channel, voltage-dependent, beta 1 subunit
Other gene symbolsCAB1 CACNLB1 CCHLB1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005245Voltage-gated calcium channel activityTASmolecular_function
GO:0005891Voltage-gated calcium channel complexIEAcellular_component
GO:0006612Protein targeting to membraneIEAbiological_process
GO:0006810TransportTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008331High voltage-gated calcium channel activityIEAmolecular_function
GO:0016529Sarcoplasmic reticulumIEAcellular_component
GO:0030315T-tubuleIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94210902320.50036609930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0811394613
GSE13712_SHEARDown-0.0214337570
GSE13712_STATICDown-0.1401364796
GSE19018Down-0.1422114486
GSE19899_A1Down-0.0590416801
GSE19899_A2Up0.0790545661
PubMed_21979375_A1Down-0.1270767043
PubMed_21979375_A2Down-0.0747962033
GSE35957Up0.0866346994
GSE36640Up0.1793998680
GSE54402Down-0.0893852658
GSE9593Up0.0081454179
GSE43922Up0.0907453741
GSE24585Down-0.1350987857
GSE37065Down-0.1182826759
GSE28863_A1Down-0.0612237149
GSE28863_A2Down-0.0872673321
GSE28863_A3Up0.0582303646
GSE28863_A4Down-0.0121639678
GSE48662Down-0.0176528361

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IbutilideDB00308 APRD01025
Magnesium SulfateDB00653 APRD01080
VerapamilDB00661 APRD00335
MibefradilDB01388 -
DronedaroneDB04855 -
SpironolactoneDB00421 APRD01234

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT021151SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.