HCSGD entry for CACNB1

1. General information

Official gene symbolCACNB1
Entrez ID782
Gene full namecalcium channel, voltage-dependent, beta 1 subunit
Other gene symbolsCAB1 CACNLB1 CCHLB1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005245Voltage-gated calcium channel activityTASmolecular_function
GO:0005891Voltage-gated calcium channel complexIEAcellular_component
GO:0006612Protein targeting to membraneIEAbiological_process
GO:0006810TransportTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008331High voltage-gated calcium channel activityIEAmolecular_function
GO:0016529Sarcoplasmic reticulumIEAcellular_component
GO:0030315T-tubuleIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94210902320.50036609930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0811394613
GSE13712_SHEARDown-0.0214337570
GSE13712_STATICDown-0.1401364796
GSE19018Down-0.1422114486
GSE19899_A1Down-0.0590416801
GSE19899_A2Up0.0790545661
PubMed_21979375_A1Down-0.1270767043
PubMed_21979375_A2Down-0.0747962033
GSE35957Up0.0866346994
GSE36640Up0.1793998680
GSE54402Down-0.0893852658
GSE9593Up0.0081454179
GSE43922Up0.0907453741
GSE24585Down-0.1350987857
GSE37065Down-0.1182826759
GSE28863_A1Down-0.0612237149
GSE28863_A2Down-0.0872673321
GSE28863_A3Up0.0582303646
GSE28863_A4Down-0.0121639678
GSE48662Down-0.0176528361

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IbutilideDB00308 APRD01025
Magnesium SulfateDB00653 APRD01080
VerapamilDB00661 APRD00335
MibefradilDB01388 -
DronedaroneDB04855 -
SpironolactoneDB00421 APRD01234

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT021151SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.