HCSGD entry for CACNA1S

1. General information

Official gene symbolCACNA1S
Entrez ID779
Gene full namecalcium channel, voltage-dependent, L type, alpha 1S subunit
Other gene symbolsCACNL1A3 CCHL1A3 Cav1.1 HOKPP HOKPP1 MHS5 TTPP1 hypoPP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentIEAbiological_process
GO:0002074Extraocular skeletal muscle developmentIEAbiological_process
GO:0005245Voltage-gated calcium channel activityIDA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005891Voltage-gated calcium channel complexIDA IEAcellular_component
GO:0006816Calcium ion transportIDAbiological_process
GO:0006936Muscle contractionIMPbiological_process
GO:0006941Striated muscle contractionIEAbiological_process
GO:0007029Endoplasmic reticulum organizationIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0007520Myoblast fusionIEAbiological_process
GO:0007528Neuromuscular junction developmentIEAbiological_process
GO:0008331High voltage-gated calcium channel activityIDAmolecular_function
GO:0016529Sarcoplasmic reticulumIEAcellular_component
GO:0030315T-tubuleIDAcellular_component
GO:0031674I bandIDAcellular_component
GO:0043501Skeletal muscle adaptationIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048741Skeletal muscle fiber developmentIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.42743471750.95061404200.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2374638242
GSE13712_SHEARDown-0.1109546922
GSE13712_STATICUp0.0299225051
GSE19018Up0.0234055042
GSE19899_A1Up0.1002846164
GSE19899_A2Up0.1666729246
PubMed_21979375_A1Up0.0342717214
PubMed_21979375_A2Up0.0471650355
GSE35957Up0.4137441689
GSE36640Up0.0712507951
GSE54402Up0.1685769368
GSE9593Down-0.0298610738
GSE43922Up0.0168543487
GSE24585Up0.0410517143
GSE37065Down-0.0282009568
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0432226465

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IsradipineDB00270 APRD00298
NisoldipineDB00401 APRD00635
CinnarizineDB00568 APRD00332
Magnesium SulfateDB00653 APRD01080
VerapamilDB00661 APRD00335
NitrendipineDB01054 APRD00421
NifedipineDB01115 APRD00590
MibefradilDB01388 -
DronedaroneDB04855 -
ClevidipineDB04920 -
NilvadipineDB06712 -
SpironolactoneDB00421 APRD01234

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029696MicroarrayFunctional MTI (Weak)19088304
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.