HCSGD entry for VRK1

1. General information

Official gene symbolVRK1
Entrez ID7443
Gene full namevaccinia related kinase 1
Other gene symbolsPCH1 PCH1A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0004674Protein serine/threonine kinase activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005795Golgi stackIDAcellular_component
GO:0005819SpindleIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0007067MitosisIEAbiological_process
GO:0007077Mitotic nuclear envelope disassemblyTASbiological_process
GO:0007084Mitotic nuclear envelope reassemblyTASbiological_process
GO:0016772Transferase activity, transferring phosphorus-containing groupsIEAmolecular_function
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0090166Golgi disassemblyIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98366858780.00235983060.99999024730.0943968085

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3903521041
GSE13712_SHEARDown-0.7151812485
GSE13712_STATICDown-0.2294925768
GSE19018Up0.0182295021
GSE19899_A1Down-0.5020152397
GSE19899_A2Down-0.9874563129
PubMed_21979375_A1Down-0.0051152651
PubMed_21979375_A2Down-1.3017419742
GSE35957Down-2.0213617112
GSE36640Down-2.4578959821
GSE54402Up0.1805777925
GSE9593Down-0.9675368131
GSE43922Down-0.2755946313
GSE24585Down-0.2191139985
GSE37065Down-0.2950123089
GSE28863_A1Down-0.1082825081
GSE28863_A2Up0.1849190326
GSE28863_A3Down-0.0359982350
GSE28863_A4Up0.1404792813
GSE48662Down-0.9093653729

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-24-3pMIMAT0000080MIRT030361MicroarrayFunctional MTI (Weak)19748357
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.