HCSGD entry for VRK1
1. General information
| Official gene symbol | VRK1 |
|---|---|
| Entrez ID | 7443 |
| Gene full name | vaccinia related kinase 1 |
| Other gene symbols | PCH1 PCH1A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005795 | Golgi stack | IDA | cellular_component |
| GO:0005819 | Spindle | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007077 | Mitotic nuclear envelope disassembly | TAS | biological_process |
| GO:0007084 | Mitotic nuclear envelope reassembly | TAS | biological_process |
| GO:0016772 | Transferase activity, transferring phosphorus-containing groups | IEA | molecular_function |
| GO:0046777 | Protein autophosphorylation | IDA | biological_process |
| GO:0090166 | Golgi disassembly | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9836685878 | 0.0023598306 | 0.9999902473 | 0.0943968085 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3903521041 |
| GSE13712_SHEAR | Down | -0.7151812485 |
| GSE13712_STATIC | Down | -0.2294925768 |
| GSE19018 | Up | 0.0182295021 |
| GSE19899_A1 | Down | -0.5020152397 |
| GSE19899_A2 | Down | -0.9874563129 |
| PubMed_21979375_A1 | Down | -0.0051152651 |
| PubMed_21979375_A2 | Down | -1.3017419742 |
| GSE35957 | Down | -2.0213617112 |
| GSE36640 | Down | -2.4578959821 |
| GSE54402 | Up | 0.1805777925 |
| GSE9593 | Down | -0.9675368131 |
| GSE43922 | Down | -0.2755946313 |
| GSE24585 | Down | -0.2191139985 |
| GSE37065 | Down | -0.2950123089 |
| GSE28863_A1 | Down | -0.1082825081 |
| GSE28863_A2 | Up | 0.1849190326 |
| GSE28863_A3 | Down | -0.0359982350 |
| GSE28863_A4 | Up | 0.1404792813 |
| GSE48662 | Down | -0.9093653729 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030361 | Microarray | Functional MTI (Weak) | 19748357 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
