HCSGD entry for UQCRB

1. General information

Official gene symbolUQCRB
Entrez ID7381
Gene full nameubiquinol-cytochrome c reductase binding protein
Other gene symbolsMC3DN3 QCR7 QP-C QPC UQBC UQBP UQCR6 UQPC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005746Mitochondrial respiratory chainTAScellular_component
GO:0005750Mitochondrial respiratory chain complex IIIIEAcellular_component
GO:0006119Oxidative phosphorylationTASbiological_process
GO:0006122Mitochondrial electron transport, ubiquinol to cytochrome cIEAbiological_process
GO:0009060Aerobic respirationTASbiological_process
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055114Oxidation-reduction processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58893721360.47944691690.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0958670069
GSE13712_SHEARDown-0.3255404188
GSE13712_STATICDown-0.1980784480
GSE19018Down-0.3241783161
GSE19899_A1Up0.2096079112
GSE19899_A2Up0.2123324755
PubMed_21979375_A1Down-0.1229518022
PubMed_21979375_A2Up0.1635473903
GSE35957Down-0.0336881336
GSE36640Up0.3095138325
GSE54402Up0.3059298235
GSE9593Down-0.0484183539
GSE43922Up0.0532852432
GSE24585Down-0.4523997372
GSE37065Up0.0927649115
GSE28863_A1Down-0.0162629477
GSE28863_A2Down-0.0762054006
GSE28863_A3Down-0.1769816756
GSE28863_A4Down-0.0513954103
GSE48662Up0.0966106705

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-TriolDB04141 EXPT00697
5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazoleDB04799 -
METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATEDB07401 -
5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONEDB07636 -
(5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONEDB07763 -
FAMOXADONEDB07778 -
METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATEDB08330 -
2-NONYL-4-HYDROXYQUINOLINE N-OXIDEDB08453 -
UBIQUINONE-2DB08690 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-423-3pMIMAT0001340MIRT042467CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.