HCSGD entry for UQCRB

1. General information

Official gene symbolUQCRB
Entrez ID7381
Gene full nameubiquinol-cytochrome c reductase binding protein
Other gene symbolsMC3DN3 QCR7 QP-C QPC UQBC UQBP UQCR6 UQPC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005746Mitochondrial respiratory chainTAScellular_component
GO:0005750Mitochondrial respiratory chain complex IIIIEAcellular_component
GO:0006119Oxidative phosphorylationTASbiological_process
GO:0006122Mitochondrial electron transport, ubiquinol to cytochrome cIEAbiological_process
GO:0009060Aerobic respirationTASbiological_process
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055114Oxidation-reduction processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58893721360.47944691690.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0958670069
GSE13712_SHEARDown-0.3255404188
GSE13712_STATICDown-0.1980784480
GSE19018Down-0.3241783161
GSE19899_A1Up0.2096079112
GSE19899_A2Up0.2123324755
PubMed_21979375_A1Down-0.1229518022
PubMed_21979375_A2Up0.1635473903
GSE35957Down-0.0336881336
GSE36640Up0.3095138325
GSE54402Up0.3059298235
GSE9593Down-0.0484183539
GSE43922Up0.0532852432
GSE24585Down-0.4523997372
GSE37065Up0.0927649115
GSE28863_A1Down-0.0162629477
GSE28863_A2Down-0.0762054006
GSE28863_A3Down-0.1769816756
GSE28863_A4Down-0.0513954103
GSE48662Up0.0966106705

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-TriolDB04141 EXPT00697
5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazoleDB04799 -
METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATEDB07401 -
5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONEDB07636 -
(5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONEDB07763 -
FAMOXADONEDB07778 -
METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATEDB08330 -
2-NONYL-4-HYDROXYQUINOLINE N-OXIDEDB08453 -
UBIQUINONE-2DB08690 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-423-3pMIMAT0001340MIRT042467CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.