HCSGD entry for UBE2E2


1. General information

Official gene symbolUBE2E2
Entrez ID7325
Gene full nameubiquitin-conjugating enzyme E2E 2
Other gene symbolsUBCH8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0016881Acid-amino acid ligase activityIEAmolecular_function
GO:0032020ISG15-protein conjugationIDAbiological_process
GO:0042296ISG15 ligase activityIDAmolecular_function
GO:0070534Protein K63-linked ubiquitinationIDAbiological_process
GO:0070936Protein K48-linked ubiquitinationIDAbiological_process
GO:0070979Protein K11-linked ubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03977371680.93633563310.44812623021.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2144629541
GSE13712_SHEARUp0.5700173364
GSE13712_STATICUp0.5263191655
GSE19018Up0.3873480979
GSE19899_A1Up0.0428827238
GSE19899_A2Up1.0183647951
PubMed_21979375_A1Up0.4693882676
PubMed_21979375_A2Up0.4153334698
GSE35957Up0.6646907182
GSE36640Up0.4434103925
GSE54402Up0.0526635061
GSE9593Up0.7546780999
GSE43922Up0.0010535602
GSE24585Down-0.3318281347
GSE37065Down-0.0056767835
GSE28863_A1Down-0.0763254002
GSE28863_A2Down-0.1415060341
GSE28863_A3Up0.0043329729
GSE28863_A4Down-0.0297766087
GSE48662Up0.1222458812

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT045236CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045536CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.