HCSGD entry for UBE2E2
1. General information
| Official gene symbol | UBE2E2 |
|---|---|
| Entrez ID | 7325 |
| Gene full name | ubiquitin-conjugating enzyme E2E 2 |
| Other gene symbols | UBCH8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
| GO:0032020 | ISG15-protein conjugation | IDA | biological_process |
| GO:0042296 | ISG15 ligase activity | IDA | molecular_function |
| GO:0070534 | Protein K63-linked ubiquitination | IDA | biological_process |
| GO:0070936 | Protein K48-linked ubiquitination | IDA | biological_process |
| GO:0070979 | Protein K11-linked ubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0397737168 | 0.9363356331 | 0.4481262302 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2144629541 |
| GSE13712_SHEAR | Up | 0.5700173364 |
| GSE13712_STATIC | Up | 0.5263191655 |
| GSE19018 | Up | 0.3873480979 |
| GSE19899_A1 | Up | 0.0428827238 |
| GSE19899_A2 | Up | 1.0183647951 |
| PubMed_21979375_A1 | Up | 0.4693882676 |
| PubMed_21979375_A2 | Up | 0.4153334698 |
| GSE35957 | Up | 0.6646907182 |
| GSE36640 | Up | 0.4434103925 |
| GSE54402 | Up | 0.0526635061 |
| GSE9593 | Up | 0.7546780999 |
| GSE43922 | Up | 0.0010535602 |
| GSE24585 | Down | -0.3318281347 |
| GSE37065 | Down | -0.0056767835 |
| GSE28863_A1 | Down | -0.0763254002 |
| GSE28863_A2 | Down | -0.1415060341 |
| GSE28863_A3 | Up | 0.0043329729 |
| GSE28863_A4 | Down | -0.0297766087 |
| GSE48662 | Up | 0.1222458812 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT045236 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045536 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
