HCSGD entry for TRH
1. General information
| Official gene symbol | TRH |
|---|---|
| Entrez ID | 7200 |
| Gene full name | thyrotropin-releasing hormone |
| Other gene symbols | TRF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IEA | biological_process |
| GO:0001692 | Histamine metabolic process | IEA | biological_process |
| GO:0005184 | Neuropeptide hormone activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA TAS | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0007628 | Adult walking behavior | IEA | biological_process |
| GO:0008437 | Thyrotropin-releasing hormone activity | IEA | molecular_function |
| GO:0009409 | Response to cold | IEA | biological_process |
| GO:0009749 | Response to glucose | IEA | biological_process |
| GO:0009755 | Hormone-mediated signaling pathway | IEA | biological_process |
| GO:0014050 | Negative regulation of glutamate secretion | IEA | biological_process |
| GO:0014054 | Positive regulation of gamma-aminobutyric acid secretion | IEA | biological_process |
| GO:0030141 | Secretory granule | IEA | cellular_component |
| GO:0032024 | Positive regulation of insulin secretion | IEA | biological_process |
| GO:0042755 | Eating behavior | IEA | biological_process |
| GO:0045471 | Response to ethanol | IEA | biological_process |
| GO:0051412 | Response to corticosterone | IEA | biological_process |
| GO:2000252 | Negative regulation of feeding behavior | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2311386232 | 0.7517889024 | 0.9146752556 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0173771954 |
| GSE13712_SHEAR | Down | -0.0306650588 |
| GSE13712_STATIC | Up | 0.0264087163 |
| GSE19018 | Up | 0.1811927339 |
| GSE19899_A1 | Up | 0.1726199903 |
| GSE19899_A2 | Up | 0.0249725781 |
| PubMed_21979375_A1 | Up | 0.1735329967 |
| PubMed_21979375_A2 | Down | -0.1672695257 |
| GSE35957 | Up | 0.4507256413 |
| GSE36640 | Up | 0.0529917311 |
| GSE54402 | Down | -0.2321062659 |
| GSE9593 | Up | 0.3233157938 |
| GSE43922 | Up | 0.0070334992 |
| GSE24585 | Up | 0.0956874379 |
| GSE37065 | Up | 0.0101446376 |
| GSE28863_A1 | Down | -0.1137675182 |
| GSE28863_A2 | Down | -0.0352562632 |
| GSE28863_A3 | Up | 0.1498595068 |
| GSE28863_A4 | Up | 0.0071757026 |
| GSE48662 | Up | 1.2795686391 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 9818729 | Coincubation of thymulin with TRH revealed a synergistic release of PRL and TSH in AP cells from all age groups |
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