HCSGD entry for TGM3

1. General information

Official gene symbolTGM3
Entrez ID7053
Gene full nametransglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
Other gene symbolsTGE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003810Protein-glutamine gamma-glutamyltransferase activityIDAmolecular_function
GO:0003824Catalytic activityIDAmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0006464Cellular protein modification processNASbiological_process
GO:0016746Transferase activity, transferring acyl groupsTASmolecular_function
GO:0018149Peptide cross-linkingIDAbiological_process
GO:0030216Keratinocyte differentiationIEP TASbiological_process
GO:0031069Hair follicle morphogenesisTASbiological_process
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIDAcellular_component
GO:0031424KeratinizationIEAbiological_process
GO:0043163Cell envelope organizationIDAbiological_process
GO:0051262Protein tetramerizationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23614723220.96300400060.91979631601.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0926555690
GSE13712_SHEARUp0.1631734761
GSE13712_STATICUp0.0878802911
GSE19018Up0.0966178154
GSE19899_A1Down-0.0156621751
GSE19899_A2Up0.3901234506
PubMed_21979375_A1Up0.1032589284
PubMed_21979375_A2Up0.0659258603
GSE35957Up0.2245403325
GSE36640Up0.2184635631
GSE54402Up0.0325231331
GSE9593Up0.1591442270
GSE43922Up0.1540997973
GSE24585Up0.0175420795
GSE37065Down-0.0849914238
GSE28863_A1Up0.0895027784
GSE28863_A2Down-0.0578484285
GSE28863_A3Up0.3978044664
GSE28863_A4Up0.0723283455
GSE48662Up0.0423785288

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

5'-Guanosine-Diphosphate-MonothiophosphateDB01864 EXPT01651
Guanosine-5'-MonophosphateDB01972 EXPT00246
B-2-OctylglucosideDB03152 EXPT00687
Guanosine-5'-DiphosphateDB04315 EXPT01573

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.