HCSGD entry for TGM3

1. General information

Official gene symbolTGM3
Entrez ID7053
Gene full nametransglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
Other gene symbolsTGE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003810Protein-glutamine gamma-glutamyltransferase activityIDAmolecular_function
GO:0003824Catalytic activityIDAmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0006464Cellular protein modification processNASbiological_process
GO:0016746Transferase activity, transferring acyl groupsTASmolecular_function
GO:0018149Peptide cross-linkingIDAbiological_process
GO:0030216Keratinocyte differentiationIEP TASbiological_process
GO:0031069Hair follicle morphogenesisTASbiological_process
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIDAcellular_component
GO:0031424KeratinizationIEAbiological_process
GO:0043163Cell envelope organizationIDAbiological_process
GO:0051262Protein tetramerizationIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23614723220.96300400060.91979631601.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0926555690
GSE13712_SHEARUp0.1631734761
GSE13712_STATICUp0.0878802911
GSE19018Up0.0966178154
GSE19899_A1Down-0.0156621751
GSE19899_A2Up0.3901234506
PubMed_21979375_A1Up0.1032589284
PubMed_21979375_A2Up0.0659258603
GSE35957Up0.2245403325
GSE36640Up0.2184635631
GSE54402Up0.0325231331
GSE9593Up0.1591442270
GSE43922Up0.1540997973
GSE24585Up0.0175420795
GSE37065Down-0.0849914238
GSE28863_A1Up0.0895027784
GSE28863_A2Down-0.0578484285
GSE28863_A3Up0.3978044664
GSE28863_A4Up0.0723283455
GSE48662Up0.0423785288

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

5'-Guanosine-Diphosphate-MonothiophosphateDB01864 EXPT01651
Guanosine-5'-MonophosphateDB01972 EXPT00246
B-2-OctylglucosideDB03152 EXPT00687
Guanosine-5'-DiphosphateDB04315 EXPT01573

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.