HCSGD entry for TAF4B

1. General information

Official gene symbolTAF4B
Entrez ID6875
Gene full nameTAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
Other gene symbolsTAF2C2 TAFII105
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIDAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005669Transcription factor TFIID complexIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006352DNA-templated transcription, initiationIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0051059NF-kappaB bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01265244100.91759473800.28103367091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1816262284
GSE13712_SHEARUp0.1419427259
GSE13712_STATICDown-0.2841012621
GSE19018Up0.1974977706
GSE19899_A1Up0.2774938850
GSE19899_A2Up1.3992686999
PubMed_21979375_A1Up2.2161452494
PubMed_21979375_A2Up1.4526627373
GSE35957Down-0.0368918434
GSE36640Down-0.1186975928
GSE54402Up0.3630263175
GSE9593Up0.1127736247
GSE43922Up1.2699500817
GSE24585Down-0.7728711743
GSE37065Up0.1070687442
GSE28863_A1Up0.0994227087
GSE28863_A2Up0.3087677662
GSE28863_A3Up0.1114120845
GSE28863_A4Down-0.0688942207
GSE48662Up0.0040740806

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-197-3pMIMAT0000227MIRT004175MicroarrayFunctional MTI (Weak)16822819
hsa-miR-26b-5pMIMAT0000083MIRT029373MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.