HCSGD entry for TAF4B
1. General information
| Official gene symbol | TAF4B |
|---|---|
| Entrez ID | 6875 |
| Gene full name | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| Other gene symbols | TAF2C2 TAFII105 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005669 | Transcription factor TFIID complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006352 | DNA-templated transcription, initiation | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
| GO:0051059 | NF-kappaB binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0126524410 | 0.9175947380 | 0.2810336709 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1816262284 |
| GSE13712_SHEAR | Up | 0.1419427259 |
| GSE13712_STATIC | Down | -0.2841012621 |
| GSE19018 | Up | 0.1974977706 |
| GSE19899_A1 | Up | 0.2774938850 |
| GSE19899_A2 | Up | 1.3992686999 |
| PubMed_21979375_A1 | Up | 2.2161452494 |
| PubMed_21979375_A2 | Up | 1.4526627373 |
| GSE35957 | Down | -0.0368918434 |
| GSE36640 | Down | -0.1186975928 |
| GSE54402 | Up | 0.3630263175 |
| GSE9593 | Up | 0.1127736247 |
| GSE43922 | Up | 1.2699500817 |
| GSE24585 | Down | -0.7728711743 |
| GSE37065 | Up | 0.1070687442 |
| GSE28863_A1 | Up | 0.0994227087 |
| GSE28863_A2 | Up | 0.3087677662 |
| GSE28863_A3 | Up | 0.1114120845 |
| GSE28863_A4 | Down | -0.0688942207 |
| GSE48662 | Up | 0.0040740806 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004175 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029373 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
