HCSGD entry for TACR1

1. General information

Official gene symbolTACR1
Entrez ID6869
Gene full nametachykinin receptor 1
Other gene symbolsNK1R NKIR SPR TAC1R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002118Aggressive behaviorIEAbiological_process
GO:0002526Acute inflammatory responseIEAbiological_process
GO:0002687Positive regulation of leukocyte migrationIEAbiological_process
GO:0003051Angiotensin-mediated drinking behaviorIEAbiological_process
GO:0004995Tachykinin receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006954Inflammatory responseTASbiological_process
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007217Tachykinin receptor signaling pathwayIDAbiological_process
GO:0007218Neuropeptide signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007610BehaviorTASbiological_process
GO:0007616Long-term memoryIEAbiological_process
GO:0007638Mechanosensory behaviorTASbiological_process
GO:0008306Associative learningIEAbiological_process
GO:0009408Response to heatIEAbiological_process
GO:0009582Detection of abiotic stimulusTASbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0010193Response to ozoneIEAbiological_process
GO:0010634Positive regulation of epithelial cell migrationIEAbiological_process
GO:0010996Response to auditory stimulusIEAbiological_process
GO:0014910Regulation of smooth muscle cell migrationIEAbiological_process
GO:0016496Substance P receptor activityIEAmolecular_function
GO:0030425DendriteIEAcellular_component
GO:0032224Positive regulation of synaptic transmission, cholinergicIEAbiological_process
GO:0032230Positive regulation of synaptic transmission, GABAergicIEAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0032570Response to progesteroneIEAbiological_process
GO:0035094Response to nicotineIEAbiological_process
GO:0035106Operant conditioningIEAbiological_process
GO:0035815Positive regulation of renal sodium excretionIEAbiological_process
GO:0042713Sperm ejaculationIEAbiological_process
GO:0042755Eating behaviorIEAbiological_process
GO:0043117Positive regulation of vascular permeabilityIEAbiological_process
GO:0043278Response to morphineIEAbiological_process
GO:0044297Cell bodyIEAcellular_component
GO:0045471Response to ethanolIEAbiological_process
GO:0045760Positive regulation of action potentialIEAbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0045778Positive regulation of ossificationIEAbiological_process
GO:0045907Positive regulation of vasoconstrictionIEAbiological_process
GO:0046878Positive regulation of saliva secretionIEAbiological_process
GO:0046887Positive regulation of hormone secretionIEAbiological_process
GO:0048266Behavioral response to painIEAbiological_process
GO:0048660Regulation of smooth muscle cell proliferationIEAbiological_process
GO:0050671Positive regulation of lymphocyte proliferationIEAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0051496Positive regulation of stress fiber assemblyIEAbiological_process
GO:0060083Smooth muscle contraction involved in micturitionIEAbiological_process
GO:0070474Positive regulation of uterine smooth muscle contractionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72419423650.87989847650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0926642540
GSE13712_SHEARDown-0.0520443924
GSE13712_STATICDown-0.0553377086
GSE19018Up0.0565683650
GSE19899_A1Down-0.0186632875
GSE19899_A2Down-0.1182959991
PubMed_21979375_A1Down-0.0554420889
PubMed_21979375_A2Down-0.1201611806
GSE35957Down-0.0453086534
GSE36640Up0.3340582101
GSE54402Up0.0416635682
GSE9593Up0.0699950146
GSE43922Up0.0141587915
GSE24585Up0.3246845473
GSE37065Down-0.0004471181
GSE28863_A1Down-0.1584559739
GSE28863_A2Up0.0883838371
GSE28863_A3Up0.1322571627
GSE28863_A4Up0.0679948304
GSE48662Up0.0605876327

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AprepitantDB00673 APRD00100
KetamineDB01221 APRD00493
VapreotideDB04894 -
AV608DB05072 -
GW 597599DB05418 -
CP-122721DB05421 -
R673DB05466 -
SR 140333DB05790 -
NetupitantDB09048 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.