HCSGD entry for TACR1

1. General information

Official gene symbolTACR1
Entrez ID6869
Gene full nametachykinin receptor 1
Other gene symbolsNK1R NKIR SPR TAC1R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002118Aggressive behaviorIEAbiological_process
GO:0002526Acute inflammatory responseIEAbiological_process
GO:0002687Positive regulation of leukocyte migrationIEAbiological_process
GO:0003051Angiotensin-mediated drinking behaviorIEAbiological_process
GO:0004995Tachykinin receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006954Inflammatory responseTASbiological_process
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007217Tachykinin receptor signaling pathwayIDAbiological_process
GO:0007218Neuropeptide signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007610BehaviorTASbiological_process
GO:0007616Long-term memoryIEAbiological_process
GO:0007638Mechanosensory behaviorTASbiological_process
GO:0008306Associative learningIEAbiological_process
GO:0009408Response to heatIEAbiological_process
GO:0009582Detection of abiotic stimulusTASbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0010193Response to ozoneIEAbiological_process
GO:0010634Positive regulation of epithelial cell migrationIEAbiological_process
GO:0010996Response to auditory stimulusIEAbiological_process
GO:0014910Regulation of smooth muscle cell migrationIEAbiological_process
GO:0016496Substance P receptor activityIEAmolecular_function
GO:0030425DendriteIEAcellular_component
GO:0032224Positive regulation of synaptic transmission, cholinergicIEAbiological_process
GO:0032230Positive regulation of synaptic transmission, GABAergicIEAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0032570Response to progesteroneIEAbiological_process
GO:0035094Response to nicotineIEAbiological_process
GO:0035106Operant conditioningIEAbiological_process
GO:0035815Positive regulation of renal sodium excretionIEAbiological_process
GO:0042713Sperm ejaculationIEAbiological_process
GO:0042755Eating behaviorIEAbiological_process
GO:0043117Positive regulation of vascular permeabilityIEAbiological_process
GO:0043278Response to morphineIEAbiological_process
GO:0044297Cell bodyIEAcellular_component
GO:0045471Response to ethanolIEAbiological_process
GO:0045760Positive regulation of action potentialIEAbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0045778Positive regulation of ossificationIEAbiological_process
GO:0045907Positive regulation of vasoconstrictionIEAbiological_process
GO:0046878Positive regulation of saliva secretionIEAbiological_process
GO:0046887Positive regulation of hormone secretionIEAbiological_process
GO:0048266Behavioral response to painIEAbiological_process
GO:0048660Regulation of smooth muscle cell proliferationIEAbiological_process
GO:0050671Positive regulation of lymphocyte proliferationIEAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0051496Positive regulation of stress fiber assemblyIEAbiological_process
GO:0060083Smooth muscle contraction involved in micturitionIEAbiological_process
GO:0070474Positive regulation of uterine smooth muscle contractionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72419423650.87989847650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0926642540
GSE13712_SHEARDown-0.0520443924
GSE13712_STATICDown-0.0553377086
GSE19018Up0.0565683650
GSE19899_A1Down-0.0186632875
GSE19899_A2Down-0.1182959991
PubMed_21979375_A1Down-0.0554420889
PubMed_21979375_A2Down-0.1201611806
GSE35957Down-0.0453086534
GSE36640Up0.3340582101
GSE54402Up0.0416635682
GSE9593Up0.0699950146
GSE43922Up0.0141587915
GSE24585Up0.3246845473
GSE37065Down-0.0004471181
GSE28863_A1Down-0.1584559739
GSE28863_A2Up0.0883838371
GSE28863_A3Up0.1322571627
GSE28863_A4Up0.0679948304
GSE48662Up0.0605876327

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AprepitantDB00673 APRD00100
KetamineDB01221 APRD00493
VapreotideDB04894 -
AV608DB05072 -
GW 597599DB05418 -
CP-122721DB05421 -
R673DB05466 -
SR 140333DB05790 -
NetupitantDB09048 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.