HCSGD entry for SSTR2

1. General information

Official gene symbolSSTR2
Entrez ID6752
Gene full namesomatostatin receptor 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004994Somatostatin receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006937Regulation of muscle contractionIEAbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0007584Response to nutrientTASbiological_process
GO:0007586DigestionTASbiological_process
GO:0008285Negative regulation of cell proliferationTASbiological_process
GO:0021549Cerebellum developmentIEAbiological_process
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030432PeristalsisIEAbiological_process
GO:0030900Forebrain developmentIEAbiological_process
GO:0042594Response to starvationIEAbiological_process
GO:0071385Cellular response to glucocorticoid stimulusIEAbiological_process
GO:0071392Cellular response to estradiol stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56295032100.77403591430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0590200004
GSE13712_SHEARDown-0.1276419727
GSE13712_STATICUp0.1231789238
GSE19018Up0.0515115528
GSE19899_A1Down-0.0458621299
GSE19899_A2Up0.0271253565
PubMed_21979375_A1Up0.1430060078
PubMed_21979375_A2Down-0.0416626372
GSE35957Down-0.0286060184
GSE36640Down-0.0225076684
GSE54402Down-0.0678702623
GSE9593Up0.0432328752
GSE43922Up0.1530905569
GSE24585Up0.4330511958
GSE37065Up0.1830713801
GSE28863_A1Down-0.1574736355
GSE28863_A2Down-0.1589593823
GSE28863_A3Up0.2962350638
GSE28863_A4Up0.1054160515
GSE48662Down-0.0616470451

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

OctreotideDB00104 BTD00088 | BIOD00088
VapreotideDB04894 -
PasireotideDB06663 -
LanreotideDB06791 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.