HCSGD entry for SSTR2
1. General information
| Official gene symbol | SSTR2 |
|---|---|
| Entrez ID | 6752 |
| Gene full name | somatostatin receptor 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004994 | Somatostatin receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006937 | Regulation of muscle contraction | IEA | biological_process |
| GO:0007187 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | TAS | biological_process |
| GO:0007193 | Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0007584 | Response to nutrient | TAS | biological_process |
| GO:0007586 | Digestion | TAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0021549 | Cerebellum development | IEA | biological_process |
| GO:0030165 | PDZ domain binding | IPI | molecular_function |
| GO:0030432 | Peristalsis | IEA | biological_process |
| GO:0030900 | Forebrain development | IEA | biological_process |
| GO:0042594 | Response to starvation | IEA | biological_process |
| GO:0071385 | Cellular response to glucocorticoid stimulus | IEA | biological_process |
| GO:0071392 | Cellular response to estradiol stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5629503210 | 0.7740359143 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0590200004 |
| GSE13712_SHEAR | Down | -0.1276419727 |
| GSE13712_STATIC | Up | 0.1231789238 |
| GSE19018 | Up | 0.0515115528 |
| GSE19899_A1 | Down | -0.0458621299 |
| GSE19899_A2 | Up | 0.0271253565 |
| PubMed_21979375_A1 | Up | 0.1430060078 |
| PubMed_21979375_A2 | Down | -0.0416626372 |
| GSE35957 | Down | -0.0286060184 |
| GSE36640 | Down | -0.0225076684 |
| GSE54402 | Down | -0.0678702623 |
| GSE9593 | Up | 0.0432328752 |
| GSE43922 | Up | 0.1530905569 |
| GSE24585 | Up | 0.4330511958 |
| GSE37065 | Up | 0.1830713801 |
| GSE28863_A1 | Down | -0.1574736355 |
| GSE28863_A2 | Down | -0.1589593823 |
| GSE28863_A3 | Up | 0.2962350638 |
| GSE28863_A4 | Up | 0.1054160515 |
| GSE48662 | Down | -0.0616470451 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Octreotide | DB00104 | BTD00088 | BIOD00088 |
| Vapreotide | DB04894 | - |
| Pasireotide | DB06663 | - |
| Lanreotide | DB06791 | - |

