HCSGD entry for SSR3


1. General information

Official gene symbolSSR3
Entrez ID6747
Gene full namesignal sequence receptor, gamma (translocon-associated protein gamma)
Other gene symbolsTRAPG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005784Sec61 translocon complexIEAcellular_component
GO:0006412TranslationTASbiological_process
GO:0006613Cotranslational protein targeting to membraneIEAbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0030176Integral component of endoplasmic reticulum membraneIEAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06161632920.17478361760.53809004640.8091689995

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2878358415
GSE13712_SHEARUp0.6205986292
GSE13712_STATICUp0.2857116887
GSE19018Up0.0640102885
GSE19899_A1Up0.0797212779
GSE19899_A2Up0.5638391603
PubMed_21979375_A1Up0.4785984163
PubMed_21979375_A2Up0.3395273527
GSE35957Up0.3460827125
GSE36640Up0.5182514264
GSE54402Up0.3953677317
GSE9593Up0.1290056840
GSE43922Up0.0075215267
GSE24585Down-0.5624858082
GSE37065Down-0.1417158095
GSE28863_A1Down-0.9172805659
GSE28863_A2Up0.1436812171
GSE28863_A3Down-0.8057633987
GSE28863_A4Down-0.3696105796
GSE48662Up0.1821974041

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019355MicroarrayFunctional MTI (Weak)17612493
hsa-miR-132-3pMIMAT0000426MIRT021752MicroarrayFunctional MTI (Weak)17612493
hsa-miR-122-5pMIMAT0000421MIRT023217MicroarrayFunctional MTI (Weak)17612493
hsa-miR-615-3pMIMAT0003283MIRT039643CLASHFunctional MTI (Weak)23622248
hsa-miR-125b-5pMIMAT0000423MIRT045912CLASHFunctional MTI (Weak)23622248
hsa-miR-3177-3pMIMAT0015054MIRT052802CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23466301In particular, the expression levels of 9 genes, HSP90B1, EID1, ATP2B4, DDAH1, PRNP, RAB1A, PGS5, TM4SF1 and SSR3, gradually increased during senescence
Entries Per Page
Displaying Page of