HCSGD entry for SSR3
1. General information
| Official gene symbol | SSR3 |
|---|---|
| Entrez ID | 6747 |
| Gene full name | signal sequence receptor, gamma (translocon-associated protein gamma) |
| Other gene symbols | TRAPG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005784 | Sec61 translocon complex | IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006613 | Cotranslational protein targeting to membrane | IEA | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0616163292 | 0.1747836176 | 0.5380900464 | 0.8091689995 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2878358415 |
| GSE13712_SHEAR | Up | 0.6205986292 |
| GSE13712_STATIC | Up | 0.2857116887 |
| GSE19018 | Up | 0.0640102885 |
| GSE19899_A1 | Up | 0.0797212779 |
| GSE19899_A2 | Up | 0.5638391603 |
| PubMed_21979375_A1 | Up | 0.4785984163 |
| PubMed_21979375_A2 | Up | 0.3395273527 |
| GSE35957 | Up | 0.3460827125 |
| GSE36640 | Up | 0.5182514264 |
| GSE54402 | Up | 0.3953677317 |
| GSE9593 | Up | 0.1290056840 |
| GSE43922 | Up | 0.0075215267 |
| GSE24585 | Down | -0.5624858082 |
| GSE37065 | Down | -0.1417158095 |
| GSE28863_A1 | Down | -0.9172805659 |
| GSE28863_A2 | Up | 0.1436812171 |
| GSE28863_A3 | Down | -0.8057633987 |
| GSE28863_A4 | Down | -0.3696105796 |
| GSE48662 | Up | 0.1821974041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019355 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021752 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023217 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039643 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045912 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3177-3p | MIMAT0015054 | MIRT052802 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23466301 | In particular, the expression levels of 9 genes, HSP90B1, EID1, ATP2B4, DDAH1, PRNP, RAB1A, PGS5, TM4SF1 and SSR3, gradually increased during senescence |
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