HCSGD entry for SOX11

1. General information

Official gene symbolSOX11
Entrez ID6664
Gene full nameSRY (sex determining region Y)-box 11
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0000976Transcription regulatory region sequence-specific DNA bindingISSmolecular_function
GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIDAmolecular_function
GO:0001071Nucleic acid binding transcription factor activityISSmolecular_function
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionISSmolecular_function
GO:0001105RNA polymerase II transcription coactivator activityISSmolecular_function
GO:0001158Enhancer sequence-specific DNA bindingIDAmolecular_function
GO:0001501Skeletal system developmentISSbiological_process
GO:0001822Kidney developmentIEAbiological_process
GO:0001841Neural tube formationISSbiological_process
GO:0002089Lens morphogenesis in camera-type eyeISSbiological_process
GO:0003151Outflow tract morphogenesisISSbiological_process
GO:0003211Cardiac ventricle formationISSbiological_process
GO:0003357Noradrenergic neuron differentiationISSbiological_process
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterISSbiological_process
GO:0006412TranslationIDAbiological_process
GO:0008135Translation factor activity, nucleic acid bindingIDAmolecular_function
GO:0008284Positive regulation of cell proliferationISSbiological_process
GO:0010628Positive regulation of gene expressionIMPbiological_process
GO:0010629Negative regulation of gene expressionIMPbiological_process
GO:0014003Oligodendrocyte developmentIEAbiological_process
GO:0014009Glial cell proliferationISSbiological_process
GO:0014032Neural crest cell developmentISSbiological_process
GO:0017015Regulation of transforming growth factor beta receptor signaling pathwayIEPbiological_process
GO:0021510Spinal cord developmentISSbiological_process
GO:0021782Glial cell developmentISSbiological_process
GO:0030182Neuron differentiationIEPbiological_process
GO:0030513Positive regulation of BMP signaling pathwayISSbiological_process
GO:0035332Positive regulation of hippo signalingISSbiological_process
GO:0035914Skeletal muscle cell differentiationIEAbiological_process
GO:0045666Positive regulation of neuron differentiationIMPbiological_process
GO:0045669Positive regulation of osteoblast differentiationIMPbiological_process
GO:0045778Positive regulation of ossificationIMPbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046887Positive regulation of hormone secretionISSbiological_process
GO:0048485Sympathetic nervous system developmentISSbiological_process
GO:0048557Embryonic digestive tract morphogenesisISSbiological_process
GO:0048704Embryonic skeletal system morphogenesisISSbiological_process
GO:0050672Negative regulation of lymphocyte proliferationIMPbiological_process
GO:0050769Positive regulation of neurogenesisISSbiological_process
GO:0060022Hard palate developmentISSbiological_process
GO:0060023Soft palate developmentISSbiological_process
GO:0060174Limb bud formationISSbiological_process
GO:0060253Negative regulation of glial cell proliferationIMPbiological_process
GO:0060412Ventricular septum morphogenesisISSbiological_process
GO:0060425Lung morphogenesisISSbiological_process
GO:0060548Negative regulation of cell deathISSbiological_process
GO:0060563Neuroepithelial cell differentiationISSbiological_process
GO:0061029Eyelid development in camera-type eyeISSbiological_process
GO:0061053Somite developmentISSbiological_process
GO:0061303Cornea development in camera-type eyeISSbiological_process
GO:0061386Closure of optic fissureISSbiological_process
GO:0072395Signal transduction involved in cell cycle checkpointIEPbiological_process
GO:2000648Positive regulation of stem cell proliferationIMPbiological_process
GO:2000678Negative regulation of transcription regulatory region DNA bindingISSbiological_process
GO:2001111Positive regulation of lens epithelial cell proliferationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96689776220.00103918920.99999024730.0614662921

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1662826053
GSE13712_SHEARDown-0.0185066496
GSE13712_STATICDown-0.1110616821
GSE19018Down-1.2508624250
GSE19899_A1Down-0.7963671450
GSE19899_A2Down-1.4042344321
PubMed_21979375_A1Down-1.1185201052
PubMed_21979375_A2Down-2.5516436266
GSE35957Down-2.4833694664
GSE36640Down-6.3468088644
GSE54402Up1.1383348156
GSE9593Down-0.0609228000
GSE43922Down-0.2457021589
GSE24585Down-0.1898601836
GSE37065Down-0.0370968328
GSE28863_A1Down-0.0448534333
GSE28863_A2Up0.0767686199
GSE28863_A3Up0.2402833371
GSE28863_A4Up0.0685135030
GSE48662Down-0.2876120261

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019474MicroarrayFunctional MTI (Weak)17612493
hsa-miR-128-3pMIMAT0000424MIRT022064MicroarrayFunctional MTI (Weak)17612493
hsa-miR-339-5pMIMAT0000764MIRT042780CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.