HCSGD entry for SOX11

1. General information

Official gene symbolSOX11
Entrez ID6664
Gene full nameSRY (sex determining region Y)-box 11
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0000976Transcription regulatory region sequence-specific DNA bindingISSmolecular_function
GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIDAmolecular_function
GO:0001071Nucleic acid binding transcription factor activityISSmolecular_function
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionISSmolecular_function
GO:0001105RNA polymerase II transcription coactivator activityISSmolecular_function
GO:0001158Enhancer sequence-specific DNA bindingIDAmolecular_function
GO:0001501Skeletal system developmentISSbiological_process
GO:0001822Kidney developmentIEAbiological_process
GO:0001841Neural tube formationISSbiological_process
GO:0002089Lens morphogenesis in camera-type eyeISSbiological_process
GO:0003151Outflow tract morphogenesisISSbiological_process
GO:0003211Cardiac ventricle formationISSbiological_process
GO:0003357Noradrenergic neuron differentiationISSbiological_process
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterISSbiological_process
GO:0006412TranslationIDAbiological_process
GO:0008135Translation factor activity, nucleic acid bindingIDAmolecular_function
GO:0008284Positive regulation of cell proliferationISSbiological_process
GO:0010628Positive regulation of gene expressionIMPbiological_process
GO:0010629Negative regulation of gene expressionIMPbiological_process
GO:0014003Oligodendrocyte developmentIEAbiological_process
GO:0014009Glial cell proliferationISSbiological_process
GO:0014032Neural crest cell developmentISSbiological_process
GO:0017015Regulation of transforming growth factor beta receptor signaling pathwayIEPbiological_process
GO:0021510Spinal cord developmentISSbiological_process
GO:0021782Glial cell developmentISSbiological_process
GO:0030182Neuron differentiationIEPbiological_process
GO:0030513Positive regulation of BMP signaling pathwayISSbiological_process
GO:0035332Positive regulation of hippo signalingISSbiological_process
GO:0035914Skeletal muscle cell differentiationIEAbiological_process
GO:0045666Positive regulation of neuron differentiationIMPbiological_process
GO:0045669Positive regulation of osteoblast differentiationIMPbiological_process
GO:0045778Positive regulation of ossificationIMPbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046887Positive regulation of hormone secretionISSbiological_process
GO:0048485Sympathetic nervous system developmentISSbiological_process
GO:0048557Embryonic digestive tract morphogenesisISSbiological_process
GO:0048704Embryonic skeletal system morphogenesisISSbiological_process
GO:0050672Negative regulation of lymphocyte proliferationIMPbiological_process
GO:0050769Positive regulation of neurogenesisISSbiological_process
GO:0060022Hard palate developmentISSbiological_process
GO:0060023Soft palate developmentISSbiological_process
GO:0060174Limb bud formationISSbiological_process
GO:0060253Negative regulation of glial cell proliferationIMPbiological_process
GO:0060412Ventricular septum morphogenesisISSbiological_process
GO:0060425Lung morphogenesisISSbiological_process
GO:0060548Negative regulation of cell deathISSbiological_process
GO:0060563Neuroepithelial cell differentiationISSbiological_process
GO:0061029Eyelid development in camera-type eyeISSbiological_process
GO:0061053Somite developmentISSbiological_process
GO:0061303Cornea development in camera-type eyeISSbiological_process
GO:0061386Closure of optic fissureISSbiological_process
GO:0072395Signal transduction involved in cell cycle checkpointIEPbiological_process
GO:2000648Positive regulation of stem cell proliferationIMPbiological_process
GO:2000678Negative regulation of transcription regulatory region DNA bindingISSbiological_process
GO:2001111Positive regulation of lens epithelial cell proliferationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96689776220.00103918920.99999024730.0614662921

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1662826053
GSE13712_SHEARDown-0.0185066496
GSE13712_STATICDown-0.1110616821
GSE19018Down-1.2508624250
GSE19899_A1Down-0.7963671450
GSE19899_A2Down-1.4042344321
PubMed_21979375_A1Down-1.1185201052
PubMed_21979375_A2Down-2.5516436266
GSE35957Down-2.4833694664
GSE36640Down-6.3468088644
GSE54402Up1.1383348156
GSE9593Down-0.0609228000
GSE43922Down-0.2457021589
GSE24585Down-0.1898601836
GSE37065Down-0.0370968328
GSE28863_A1Down-0.0448534333
GSE28863_A2Up0.0767686199
GSE28863_A3Up0.2402833371
GSE28863_A4Up0.0685135030
GSE48662Down-0.2876120261

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019474MicroarrayFunctional MTI (Weak)17612493
hsa-miR-128-3pMIMAT0000424MIRT022064MicroarrayFunctional MTI (Weak)17612493
hsa-miR-339-5pMIMAT0000764MIRT042780CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.