HCSGD entry for SNRPB
1. General information
| Official gene symbol | SNRPB |
|---|---|
| Entrez ID | 6628 |
| Gene full name | small nuclear ribonucleoprotein polypeptides B and B1 |
| Other gene symbols | COD SNRPB1 Sm-B/B' SmB/B' SmB/SmB' snRNP-B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000387 | Spliceosomal snRNP assembly | IDA TAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | TAS | cellular_component |
| GO:0005683 | U7 snRNP | IDA | cellular_component |
| GO:0005685 | U1 snRNP | IDA | cellular_component |
| GO:0005687 | U4 snRNP | IDA | cellular_component |
| GO:0005689 | U12-type spliceosomal complex | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0008334 | Histone mRNA metabolic process | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0030532 | Small nuclear ribonucleoprotein complex | TAS | cellular_component |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
| GO:0034660 | NcRNA metabolic process | TAS | biological_process |
| GO:0034709 | Methylosome | IDA | cellular_component |
| GO:0034719 | SMN-Sm protein complex | IDA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
| GO:0071204 | Histone pre-mRNA 3'end processing complex | IEA | cellular_component |
| GO:0071208 | Histone pre-mRNA DCP binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7282358611 | 0.0434674063 | 0.9999902473 | 0.3927163867 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2612608090 |
| GSE13712_SHEAR | Down | -0.1275758576 |
| GSE13712_STATIC | Down | -0.0974549186 |
| GSE19018 | Down | -0.5652550565 |
| GSE19899_A1 | Down | -0.1521938572 |
| GSE19899_A2 | Up | 0.0926717238 |
| PubMed_21979375_A1 | Up | 1.5132916475 |
| PubMed_21979375_A2 | Down | -0.0418543208 |
| GSE35957 | Down | -0.5677072439 |
| GSE36640 | Down | -1.3340437867 |
| GSE54402 | Up | 0.5905300704 |
| GSE9593 | Down | -0.6166066233 |
| GSE43922 | Up | 0.1198463890 |
| GSE24585 | Down | -0.0788311893 |
| GSE37065 | Down | -0.3501062315 |
| GSE28863_A1 | Down | -0.0042233767 |
| GSE28863_A2 | Down | -0.0400591689 |
| GSE28863_A3 | Down | -0.2979045677 |
| GSE28863_A4 | Up | 0.1942999891 |
| GSE48662 | Down | -0.5846091094 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022383 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041541 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044720 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045972 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
