HCSGD entry for SNRPB

1. General information

Official gene symbolSNRPB
Entrez ID6628
Gene full namesmall nuclear ribonucleoprotein polypeptides B and B1
Other gene symbolsCOD SNRPB1 Sm-B/B' SmB/B' SmB/SmB' snRNP-B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000387Spliceosomal snRNP assemblyIDA TASbiological_process
GO:0000398MRNA splicing, via spliceosomeIC TASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005681Spliceosomal complexTAScellular_component
GO:0005683U7 snRNPIDAcellular_component
GO:0005685U1 snRNPIDAcellular_component
GO:0005687U4 snRNPIDAcellular_component
GO:0005689U12-type spliceosomal complexIDAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006369Termination of RNA polymerase II transcriptionTASbiological_process
GO:0008334Histone mRNA metabolic processTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0030532Small nuclear ribonucleoprotein complexTAScellular_component
GO:0031124MRNA 3'-end processingTASbiological_process
GO:0034660NcRNA metabolic processTASbiological_process
GO:0034709MethylosomeIDAcellular_component
GO:0034719SMN-Sm protein complexIDAcellular_component
GO:0071013Catalytic step 2 spliceosomeIDAcellular_component
GO:0071204Histone pre-mRNA 3'end processing complexIEAcellular_component
GO:0071208Histone pre-mRNA DCP bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72823586110.04346740630.99999024730.3927163867

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2612608090
GSE13712_SHEARDown-0.1275758576
GSE13712_STATICDown-0.0974549186
GSE19018Down-0.5652550565
GSE19899_A1Down-0.1521938572
GSE19899_A2Up0.0926717238
PubMed_21979375_A1Up1.5132916475
PubMed_21979375_A2Down-0.0418543208
GSE35957Down-0.5677072439
GSE36640Down-1.3340437867
GSE54402Up0.5905300704
GSE9593Down-0.6166066233
GSE43922Up0.1198463890
GSE24585Down-0.0788311893
GSE37065Down-0.3501062315
GSE28863_A1Down-0.0042233767
GSE28863_A2Down-0.0400591689
GSE28863_A3Down-0.2979045677
GSE28863_A4Up0.1942999891
GSE48662Down-0.5846091094

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022383Proteomics;MicroarrayNon-Functional MTI (Weak)18668037
hsa-miR-193b-3pMIMAT0002819MIRT041541CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044720CLASHFunctional MTI (Weak)23622248
hsa-miR-125b-5pMIMAT0000423MIRT045972CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.