HCSGD entry for SIGLEC1

1. General information

Official gene symbolSIGLEC1
Entrez ID6614
Gene full namesialic acid binding Ig-like lectin 1, sialoadhesin
Other gene symbolsCD169 SIGLEC-1 SN dJ1009E24.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006897EndocytosisIEAbiological_process
GO:0006954Inflammatory responseNASbiological_process
GO:0007160Cell-matrix adhesionNASbiological_process
GO:0016021Integral component of membraneNAScellular_component
GO:0016337Cell-cell adhesionNASbiological_process
GO:0030246Carbohydrate bindingNASmolecular_function
GO:0070234Positive regulation of T cell apoptotic processIEAbiological_process
GO:2001238Positive regulation of extrinsic apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46168093920.94487843170.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0056105602
GSE13712_SHEARUp0.0303583992
GSE13712_STATICDown-0.0375722167
GSE19018Up0.1924881985
GSE19899_A1Up0.1010247164
GSE19899_A2Up0.0871516285
PubMed_21979375_A1Up0.0847421613
PubMed_21979375_A2Up0.1006068370
GSE35957Up0.0314160779
GSE36640Up0.1338562492
GSE54402Down-0.0145402815
GSE9593Up0.0692007740
GSE43922Up0.0292177275
GSE24585Up0.0564878994
GSE37065Down-0.0362769460
GSE28863_A1Down-0.0018932081
GSE28863_A2Down-0.0213526800
GSE28863_A3Up0.4605455861
GSE28863_A4Up0.0606845623
GSE48662Down-0.0959957536

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Beta-D-GlucoseDB02379 EXPT00685 | EXPT00455 | EXPT01603
N-acetyl-alpha-neuraminic acidDB03721 EXPT02292 | EXPT02908 | EXPT02909 | DB01894 | DB02344

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.