HCSGD entry for SIGLEC1
1. General information
| Official gene symbol | SIGLEC1 |
|---|---|
| Entrez ID | 6614 |
| Gene full name | sialic acid binding Ig-like lectin 1, sialoadhesin |
| Other gene symbols | CD169 SIGLEC-1 SN dJ1009E24.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0006954 | Inflammatory response | NAS | biological_process |
| GO:0007160 | Cell-matrix adhesion | NAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0016337 | Cell-cell adhesion | NAS | biological_process |
| GO:0030246 | Carbohydrate binding | NAS | molecular_function |
| GO:0070234 | Positive regulation of T cell apoptotic process | IEA | biological_process |
| GO:2001238 | Positive regulation of extrinsic apoptotic signaling pathway | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4616809392 | 0.9448784317 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0056105602 |
| GSE13712_SHEAR | Up | 0.0303583992 |
| GSE13712_STATIC | Down | -0.0375722167 |
| GSE19018 | Up | 0.1924881985 |
| GSE19899_A1 | Up | 0.1010247164 |
| GSE19899_A2 | Up | 0.0871516285 |
| PubMed_21979375_A1 | Up | 0.0847421613 |
| PubMed_21979375_A2 | Up | 0.1006068370 |
| GSE35957 | Up | 0.0314160779 |
| GSE36640 | Up | 0.1338562492 |
| GSE54402 | Down | -0.0145402815 |
| GSE9593 | Up | 0.0692007740 |
| GSE43922 | Up | 0.0292177275 |
| GSE24585 | Up | 0.0564878994 |
| GSE37065 | Down | -0.0362769460 |
| GSE28863_A1 | Down | -0.0018932081 |
| GSE28863_A2 | Down | -0.0213526800 |
| GSE28863_A3 | Up | 0.4605455861 |
| GSE28863_A4 | Up | 0.0606845623 |
| GSE48662 | Down | -0.0959957536 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Beta-D-Glucose | DB02379 | EXPT00685 | EXPT00455 | EXPT01603 |
| N-acetyl-alpha-neuraminic acid | DB03721 | EXPT02292 | EXPT02908 | EXPT02909 | DB01894 | DB02344 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
