HCSGD entry for SLC9A3

1. General information

Official gene symbolSLC9A3
Entrez ID6550
Gene full namesolute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Other gene symbolsNHE3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneISS TAScellular_component
GO:0005903Brush borderISScellular_component
GO:0006811Ion transportTASbiological_process
GO:0006885Regulation of pHIEAbiological_process
GO:0009986Cell surfaceISScellular_component
GO:0015385Sodium:hydrogen antiporter activityIEA ISSmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0030165PDZ domain bindingISSmolecular_function
GO:0031526Brush border membraneISScellular_component
GO:0034220Ion transmembrane transportISSbiological_process
GO:0035725Sodium ion transmembrane transportISSbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902600Hydrogen ion transmembrane transportISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67348444210.74546068540.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0277767665
GSE13712_SHEARDown-0.0852725447
GSE13712_STATICUp0.0141211083
GSE19018Up0.0585824217
GSE19899_A1Up0.1542729065
GSE19899_A2Up0.0035476235
PubMed_21979375_A1Down-0.1852137725
PubMed_21979375_A2Down-0.2399555600
GSE35957Up0.1547501716
GSE36640Up0.0986196197
GSE54402Up0.0131467034
GSE9593Down-0.0215079327
GSE43922Up0.0313910599
GSE24585Up0.1005369564
GSE37065Down-0.1933396142
GSE28863_A1Down-0.1345288815
GSE28863_A2Up0.0578553494
GSE28863_A3Up0.3680330166
GSE28863_A4Up0.1296786401
GSE48662Down-0.0042171661

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.