HCSGD entry for SLC9A3


1. General information

Official gene symbolSLC9A3
Entrez ID6550
Gene full namesolute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Other gene symbolsNHE3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneISS TAScellular_component
GO:0005903Brush borderISScellular_component
GO:0006811Ion transportTASbiological_process
GO:0006885Regulation of pHIEAbiological_process
GO:0009986Cell surfaceISScellular_component
GO:0015385Sodium:hydrogen antiporter activityIEA ISSmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0030165PDZ domain bindingISSmolecular_function
GO:0031526Brush border membraneISScellular_component
GO:0034220Ion transmembrane transportISSbiological_process
GO:0035725Sodium ion transmembrane transportISSbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902600Hydrogen ion transmembrane transportISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67348444210.74546068540.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0277767665
GSE13712_SHEARDown-0.0852725447
GSE13712_STATICUp0.0141211083
GSE19018Up0.0585824217
GSE19899_A1Up0.1542729065
GSE19899_A2Up0.0035476235
PubMed_21979375_A1Down-0.1852137725
PubMed_21979375_A2Down-0.2399555600
GSE35957Up0.1547501716
GSE36640Up0.0986196197
GSE54402Up0.0131467034
GSE9593Down-0.0215079327
GSE43922Up0.0313910599
GSE24585Up0.1005369564
GSE37065Down-0.1933396142
GSE28863_A1Down-0.1345288815
GSE28863_A2Up0.0578553494
GSE28863_A3Up0.3680330166
GSE28863_A4Up0.1296786401
GSE48662Down-0.0042171661

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.