HCSGD entry for SLC5A3
1. General information
| Official gene symbol | SLC5A3 |
|---|---|
| Entrez ID | 6526 |
| Gene full name | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| Other gene symbols | SMIT SMIT1 SMIT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005367 | Myo-inositol:sodium symporter activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0015791 | Polyol transport | TAS | biological_process |
| GO:0015798 | Myo-inositol transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0028968086 | 0.6804274458 | 0.1443304348 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1567512286 |
| GSE13712_SHEAR | Up | 0.4943560516 |
| GSE13712_STATIC | Down | -0.1159885409 |
| GSE19018 | Down | -0.9902445410 |
| GSE19899_A1 | Up | 2.0806345653 |
| GSE19899_A2 | Up | 0.2347299498 |
| PubMed_21979375_A1 | Up | 0.9530643692 |
| PubMed_21979375_A2 | Up | 0.5049737444 |
| GSE35957 | Down | -1.0827067955 |
| GSE36640 | Up | 0.5254673937 |
| GSE54402 | Up | 0.5122103379 |
| GSE9593 | Down | -0.4861958410 |
| GSE43922 | Up | 0.7413907048 |
| GSE24585 | Down | -0.0176662403 |
| GSE37065 | Up | 0.4023664135 |
| GSE28863_A1 | Up | 0.5901034411 |
| GSE28863_A2 | Up | 0.9630509057 |
| GSE28863_A3 | Down | -0.4825398587 |
| GSE28863_A4 | Up | 0.2599986174 |
| GSE48662 | Up | 0.4527238967 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018102 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020185 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022015 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028159 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029655 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030910 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037180 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047069 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
