HCSGD entry for SLC5A3


1. General information

Official gene symbolSLC5A3
Entrez ID6526
Gene full namesolute carrier family 5 (sodium/myo-inositol cotransporter), member 3
Other gene symbolsSMIT SMIT1 SMIT2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005367Myo-inositol:sodium symporter activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0015791Polyol transportTASbiological_process
GO:0015798Myo-inositol transportTASbiological_process
GO:0016021Integral component of membraneTAScellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00289680860.68042744580.14433043481.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1567512286
GSE13712_SHEARUp0.4943560516
GSE13712_STATICDown-0.1159885409
GSE19018Down-0.9902445410
GSE19899_A1Up2.0806345653
GSE19899_A2Up0.2347299498
PubMed_21979375_A1Up0.9530643692
PubMed_21979375_A2Up0.5049737444
GSE35957Down-1.0827067955
GSE36640Up0.5254673937
GSE54402Up0.5122103379
GSE9593Down-0.4861958410
GSE43922Up0.7413907048
GSE24585Down-0.0176662403
GSE37065Up0.4023664135
GSE28863_A1Up0.5901034411
GSE28863_A2Up0.9630509057
GSE28863_A3Down-0.4825398587
GSE28863_A4Up0.2599986174
GSE48662Up0.4527238967

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018102MicroarrayFunctional MTI (Weak)18185580
hsa-miR-130b-3pMIMAT0000691MIRT020185SequencingFunctional MTI (Weak)20371350
hsa-miR-128-3pMIMAT0000424MIRT022015SequencingFunctional MTI (Weak)20371350
hsa-miR-93-5pMIMAT0000093MIRT028159SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029655SequencingFunctional MTI (Weak)20371350
hsa-miR-21-5pMIMAT0000076MIRT030910MicroarrayFunctional MTI (Weak)18591254
hsa-miR-877-3pMIMAT0004950MIRT037180CLASHFunctional MTI (Weak)23622248
hsa-miR-183-5pMIMAT0000261MIRT047069CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.