HCSGD entry for SLC26A6

1. General information

Official gene symbolSLC26A6
Entrez ID65010
Gene full namesolute carrier family 26, member 6
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005254Chloride channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006810TransportIDAbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006820Anion transportIDAbiological_process
GO:0006821Chloride transportIDA IMPbiological_process
GO:0008271Secondary active sulfate transmembrane transporter activityIEAmolecular_function
GO:0008272Sulfate transportIMP ISSbiological_process
GO:0012506Vesicle membraneISScellular_component
GO:0015106Bicarbonate transmembrane transporter activityIDA IMP ISSmolecular_function
GO:0015108Chloride transmembrane transporter activityIDA IMP ISSmolecular_function
GO:0015116Sulfate transmembrane transporter activityIDA IEA IMPmolecular_function
GO:0015301Anion:anion antiporter activityIDA IMP ISSmolecular_function
GO:0015499Formate transmembrane transporter activityISSmolecular_function
GO:0015562Efflux transmembrane transporter activityISSmolecular_function
GO:0015659Formate uptake transmembrane transporter activityISSmolecular_function
GO:0015660Formate efflux transmembrane transporter activityISSmolecular_function
GO:0015698Inorganic anion transportIDAbiological_process
GO:0015701Bicarbonate transportIDA IMPbiological_process
GO:0015711Organic anion transportIDAbiological_process
GO:0015724Formate transportISSbiological_process
GO:0015797Mannitol transportISSbiological_process
GO:0016020MembraneISScellular_component
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0019531Oxalate transmembrane transporter activityIMPmolecular_function
GO:0019532Oxalate transportIMP ISSbiological_process
GO:0030165PDZ domain bindingISSmolecular_function
GO:0030321Transepithelial chloride transportIMP ISSbiological_process
GO:0030659Cytoplasmic vesicle membraneIEAcellular_component
GO:0031526Brush border membraneIDAcellular_component
GO:0031988Membrane-bounded vesicleISScellular_component
GO:0034220Ion transmembrane transportIDA IMP ISSbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0038166Angiotensin-activated signaling pathwayIDAbiological_process
GO:0042045Epithelial fluid transportISSbiological_process
GO:0046724Oxalic acid secretionISSbiological_process
GO:0048240Sperm capacitationISSbiological_process
GO:0050892Intestinal absorptionISSbiological_process
GO:0051453Regulation of intracellular pHIDA IMPbiological_process
GO:0051454Intracellular pH elevationISSbiological_process
GO:0055085Transmembrane transportIDA TASbiological_process
GO:0070528Protein kinase C signalingIDAbiological_process
GO:0070633Transepithelial transportISSbiological_process
GO:0071320Cellular response to cAMPISSbiological_process
GO:0071332Cellular response to fructose stimulusISSbiological_process
GO:0071346Cellular response to interferon-gammaIDAbiological_process
GO:0097225Sperm midpieceISScellular_component
GO:1902358Sulfate transmembrane transportIDA IMPbiological_process
GO:1902476Chloride transmembrane transportIDA IMP ISSbiological_process
GO:2001150Positive regulation of dipeptide transmembrane transportISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27711613540.90239190000.97403953271.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0399861924
GSE13712_SHEARUp0.4615845073
GSE13712_STATICUp0.5997122622
GSE19018Up0.0732026165
GSE19899_A1Up0.0657949522
GSE19899_A2Up0.1936515519
PubMed_21979375_A1Up0.3979831258
PubMed_21979375_A2Up0.0528249883
GSE35957Up0.2618152596
GSE36640Down-0.0659140015
GSE54402Down-0.0347129358
GSE9593Down-0.2324943231
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0702699221

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23019197However, the ratios of cystic fibrosis transmembrane conductance regulator (CFTR) and solute-linked carrier 26 gene family (Slc26a6) mRNA expression in relation to cytokeratin-18 were not altered in duodenal mucosa
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