HCSGD entry for SLC26A6

1. General information

Official gene symbolSLC26A6
Entrez ID65010
Gene full namesolute carrier family 26, member 6
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005254Chloride channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006810TransportIDAbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006820Anion transportIDAbiological_process
GO:0006821Chloride transportIDA IMPbiological_process
GO:0008271Secondary active sulfate transmembrane transporter activityIEAmolecular_function
GO:0008272Sulfate transportIMP ISSbiological_process
GO:0012506Vesicle membraneISScellular_component
GO:0015106Bicarbonate transmembrane transporter activityIDA IMP ISSmolecular_function
GO:0015108Chloride transmembrane transporter activityIDA IMP ISSmolecular_function
GO:0015116Sulfate transmembrane transporter activityIDA IEA IMPmolecular_function
GO:0015301Anion:anion antiporter activityIDA IMP ISSmolecular_function
GO:0015499Formate transmembrane transporter activityISSmolecular_function
GO:0015562Efflux transmembrane transporter activityISSmolecular_function
GO:0015659Formate uptake transmembrane transporter activityISSmolecular_function
GO:0015660Formate efflux transmembrane transporter activityISSmolecular_function
GO:0015698Inorganic anion transportIDAbiological_process
GO:0015701Bicarbonate transportIDA IMPbiological_process
GO:0015711Organic anion transportIDAbiological_process
GO:0015724Formate transportISSbiological_process
GO:0015797Mannitol transportISSbiological_process
GO:0016020MembraneISScellular_component
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0019531Oxalate transmembrane transporter activityIMPmolecular_function
GO:0019532Oxalate transportIMP ISSbiological_process
GO:0030165PDZ domain bindingISSmolecular_function
GO:0030321Transepithelial chloride transportIMP ISSbiological_process
GO:0030659Cytoplasmic vesicle membraneIEAcellular_component
GO:0031526Brush border membraneIDAcellular_component
GO:0031988Membrane-bounded vesicleISScellular_component
GO:0034220Ion transmembrane transportIDA IMP ISSbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0038166Angiotensin-activated signaling pathwayIDAbiological_process
GO:0042045Epithelial fluid transportISSbiological_process
GO:0046724Oxalic acid secretionISSbiological_process
GO:0048240Sperm capacitationISSbiological_process
GO:0050892Intestinal absorptionISSbiological_process
GO:0051453Regulation of intracellular pHIDA IMPbiological_process
GO:0051454Intracellular pH elevationISSbiological_process
GO:0055085Transmembrane transportIDA TASbiological_process
GO:0070528Protein kinase C signalingIDAbiological_process
GO:0070633Transepithelial transportISSbiological_process
GO:0071320Cellular response to cAMPISSbiological_process
GO:0071332Cellular response to fructose stimulusISSbiological_process
GO:0071346Cellular response to interferon-gammaIDAbiological_process
GO:0097225Sperm midpieceISScellular_component
GO:1902358Sulfate transmembrane transportIDA IMPbiological_process
GO:1902476Chloride transmembrane transportIDA IMP ISSbiological_process
GO:2001150Positive regulation of dipeptide transmembrane transportISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27711613540.90239190000.97403953271.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0399861924
GSE13712_SHEARUp0.4615845073
GSE13712_STATICUp0.5997122622
GSE19018Up0.0732026165
GSE19899_A1Up0.0657949522
GSE19899_A2Up0.1936515519
PubMed_21979375_A1Up0.3979831258
PubMed_21979375_A2Up0.0528249883
GSE35957Up0.2618152596
GSE36640Down-0.0659140015
GSE54402Down-0.0347129358
GSE9593Down-0.2324943231
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0702699221

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23019197However, the ratios of cystic fibrosis transmembrane conductance regulator (CFTR) and solute-linked carrier 26 gene family (Slc26a6) mRNA expression in relation to cytokeratin-18 were not altered in duodenal mucosa
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