HCSGD entry for ARAP3

1. General information

Official gene symbolARAP3
Entrez ID64411
Gene full nameArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Other gene symbolsCENTD3 DRAG1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleISScellular_component
GO:0005100Rho GTPase activator activityIEA ISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005547Phosphatidylinositol-3,4,5-trisphosphate bindingIDAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIC ISScellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007010Cytoskeleton organizationTASbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0008060ARF GTPase activator activityIEA ISSmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008360Regulation of cell shapeIEA ISSbiological_process
GO:0016192Vesicle-mediated transportTASbiological_process
GO:0030027LamellipodiumISScellular_component
GO:0030336Negative regulation of cell migrationIEA ISSbiological_process
GO:0030675Rac GTPase activator activityISSmolecular_function
GO:0032312Regulation of ARF GTPase activityIEAbiological_process
GO:0035021Negative regulation of Rac protein signal transductionIEAbiological_process
GO:0035024Negative regulation of Rho protein signal transductionIEA ISSbiological_process
GO:0043325Phosphatidylinositol-3,4-bisphosphate bindingIDAmolecular_function
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15805842480.74439278520.78882362531.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1783463740
GSE13712_SHEARUp0.5773442725
GSE13712_STATICDown-0.3009805426
GSE19018Down-0.0455482039
GSE19899_A1Up0.1408914971
GSE19899_A2Up0.3950531911
PubMed_21979375_A1Up0.0391277578
PubMed_21979375_A2Up0.4342654353
GSE35957Up0.1755200810
GSE36640Down-0.5571391399
GSE54402Up0.4371457659
GSE9593Down-0.2866209552
GSE43922Up0.0549782168
GSE24585Up0.0340020270
GSE37065Up0.0837064171
GSE28863_A1Up0.0698491084
GSE28863_A2Up0.3030487506
GSE28863_A3Up0.1345139782
GSE28863_A4Down-0.0067954157
GSE48662Down-0.0369523697

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.