HCSGD entry for ARAP3

1. General information

Official gene symbolARAP3
Entrez ID64411
Gene full nameArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Other gene symbolsCENTD3 DRAG1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleISScellular_component
GO:0005100Rho GTPase activator activityIEA ISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005547Phosphatidylinositol-3,4,5-trisphosphate bindingIDAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIC ISScellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007010Cytoskeleton organizationTASbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0008060ARF GTPase activator activityIEA ISSmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008360Regulation of cell shapeIEA ISSbiological_process
GO:0016192Vesicle-mediated transportTASbiological_process
GO:0030027LamellipodiumISScellular_component
GO:0030336Negative regulation of cell migrationIEA ISSbiological_process
GO:0030675Rac GTPase activator activityISSmolecular_function
GO:0032312Regulation of ARF GTPase activityIEAbiological_process
GO:0035021Negative regulation of Rac protein signal transductionIEAbiological_process
GO:0035024Negative regulation of Rho protein signal transductionIEA ISSbiological_process
GO:0043325Phosphatidylinositol-3,4-bisphosphate bindingIDAmolecular_function
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15805842480.74439278520.78882362531.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1783463740
GSE13712_SHEARUp0.5773442725
GSE13712_STATICDown-0.3009805426
GSE19018Down-0.0455482039
GSE19899_A1Up0.1408914971
GSE19899_A2Up0.3950531911
PubMed_21979375_A1Up0.0391277578
PubMed_21979375_A2Up0.4342654353
GSE35957Up0.1755200810
GSE36640Down-0.5571391399
GSE54402Up0.4371457659
GSE9593Down-0.2866209552
GSE43922Up0.0549782168
GSE24585Up0.0340020270
GSE37065Up0.0837064171
GSE28863_A1Up0.0698491084
GSE28863_A2Up0.3030487506
GSE28863_A3Up0.1345139782
GSE28863_A4Down-0.0067954157
GSE48662Down-0.0369523697

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.