HCSGD entry for SFRP5

1. General information

Official gene symbolSFRP5
Entrez ID6425
Gene full namesecreted frizzled-related protein 5
Other gene symbolsSARP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001944Vasculature developmentIBAbiological_process
GO:0005615Extracellular spaceTAScellular_component
GO:0005737CytoplasmIBAcellular_component
GO:0005886Plasma membraneIBAcellular_component
GO:0006915Apoptotic processTASbiological_process
GO:0007163Establishment or maintenance of cell polarityTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007420Brain developmentIBAbiological_process
GO:0007601Visual perceptionTASbiological_process
GO:0008285Negative regulation of cell proliferationIMPbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0009790Embryo developmentIBAbiological_process
GO:0017147Wnt-protein bindingIBAmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030165PDZ domain bindingIBAmolecular_function
GO:0035414Negative regulation of catenin import into nucleusIMPbiological_process
GO:0036342Post-anal tail morphogenesisIEAbiological_process
GO:0042813Wnt-activated receptor activityIBAmolecular_function
GO:0042995Cell projectionIKRcellular_component
GO:0043433Negative regulation of sequence-specific DNA binding transcription factor activityIMPbiological_process
GO:0043508Negative regulation of JUN kinase activityIEAbiological_process
GO:0048546Digestive tract morphogenesisIEAbiological_process
GO:0051898Negative regulation of protein kinase B signalingIMPbiological_process
GO:0060028Convergent extension involved in axis elongationIEAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIMPbiological_process
GO:0090179Planar cell polarity pathway involved in neural tube closureIEAbiological_process
GO:2000041Negative regulation of planar cell polarity pathway involved in axis elongationIEAbiological_process
GO:2000057Negative regulation of Wnt signaling pathway involved in digestive tract morphogenesisIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75194825420.71281652290.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0326411804
GSE13712_SHEARDown-0.1338559904
GSE13712_STATICUp0.0561695552
GSE19018Up0.0337926721
GSE19899_A1Down-0.1028811631
GSE19899_A2Up0.2328588337
PubMed_21979375_A1Down-0.0576984091
PubMed_21979375_A2Down-0.1043023052
GSE35957Up0.2127865917
GSE36640Down-0.0333088494
GSE54402Up0.0735743970
GSE9593Down-0.0356759828
GSE43922Up0.0134333310
GSE24585Down-0.0407978024
GSE37065Down-0.0876840086
GSE28863_A1Down-0.1038865768
GSE28863_A2Down-0.2026432838
GSE28863_A3Up0.3146723034
GSE28863_A4Up0.2030100287
GSE48662Up0.0529415013

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.