HCSGD entry for SFRP5

1. General information

Official gene symbolSFRP5
Entrez ID6425
Gene full namesecreted frizzled-related protein 5
Other gene symbolsSARP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001944Vasculature developmentIBAbiological_process
GO:0005615Extracellular spaceTAScellular_component
GO:0005737CytoplasmIBAcellular_component
GO:0005886Plasma membraneIBAcellular_component
GO:0006915Apoptotic processTASbiological_process
GO:0007163Establishment or maintenance of cell polarityTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007420Brain developmentIBAbiological_process
GO:0007601Visual perceptionTASbiological_process
GO:0008285Negative regulation of cell proliferationIMPbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0009790Embryo developmentIBAbiological_process
GO:0017147Wnt-protein bindingIBAmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030165PDZ domain bindingIBAmolecular_function
GO:0035414Negative regulation of catenin import into nucleusIMPbiological_process
GO:0036342Post-anal tail morphogenesisIEAbiological_process
GO:0042813Wnt-activated receptor activityIBAmolecular_function
GO:0042995Cell projectionIKRcellular_component
GO:0043433Negative regulation of sequence-specific DNA binding transcription factor activityIMPbiological_process
GO:0043508Negative regulation of JUN kinase activityIEAbiological_process
GO:0048546Digestive tract morphogenesisIEAbiological_process
GO:0051898Negative regulation of protein kinase B signalingIMPbiological_process
GO:0060028Convergent extension involved in axis elongationIEAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIMPbiological_process
GO:0090179Planar cell polarity pathway involved in neural tube closureIEAbiological_process
GO:2000041Negative regulation of planar cell polarity pathway involved in axis elongationIEAbiological_process
GO:2000057Negative regulation of Wnt signaling pathway involved in digestive tract morphogenesisIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75194825420.71281652290.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0326411804
GSE13712_SHEARDown-0.1338559904
GSE13712_STATICUp0.0561695552
GSE19018Up0.0337926721
GSE19899_A1Down-0.1028811631
GSE19899_A2Up0.2328588337
PubMed_21979375_A1Down-0.0576984091
PubMed_21979375_A2Down-0.1043023052
GSE35957Up0.2127865917
GSE36640Down-0.0333088494
GSE54402Up0.0735743970
GSE9593Down-0.0356759828
GSE43922Up0.0134333310
GSE24585Down-0.0407978024
GSE37065Down-0.0876840086
GSE28863_A1Down-0.1038865768
GSE28863_A2Down-0.2026432838
GSE28863_A3Up0.3146723034
GSE28863_A4Up0.2030100287
GSE48662Up0.0529415013

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.