HCSGD entry for UBE2O
1. General information
| Official gene symbol | UBE2O |
|---|---|
| Entrez ID | 63893 |
| Gene full name | ubiquitin-conjugating enzyme E2O |
| Other gene symbols | E2-230K |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0434469967 | 0.9822623381 | 0.4637341444 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1424585307 |
| GSE13712_SHEAR | Up | 0.1119683593 |
| GSE13712_STATIC | Up | 0.3587674122 |
| GSE19018 | Up | 0.1123583714 |
| GSE19899_A1 | Up | 0.1402098701 |
| GSE19899_A2 | Up | 0.3879487129 |
| PubMed_21979375_A1 | Up | 0.8482745683 |
| PubMed_21979375_A2 | Up | 0.5472894647 |
| GSE35957 | Up | 0.0454775313 |
| GSE36640 | Down | -0.0982248436 |
| GSE54402 | Up | 0.2778296400 |
| GSE9593 | Down | -0.0945674936 |
| GSE43922 | Up | 0.4150231417 |
| GSE24585 | Up | 0.1669709023 |
| GSE37065 | Up | 0.0203814327 |
| GSE28863_A1 | Up | 0.2279472394 |
| GSE28863_A2 | Up | 0.2321377123 |
| GSE28863_A3 | Up | 0.1047657892 |
| GSE28863_A4 | Up | 0.0897338768 |
| GSE48662 | Up | 0.3808499130 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017347 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037063 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037423 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-1-3p | MIMAT0004674 | MIRT038542 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT041058 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043811 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048803 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
