HCSGD entry for UBE2O


1. General information

Official gene symbolUBE2O
Entrez ID63893
Gene full nameubiquitin-conjugating enzyme E2O
Other gene symbolsE2-230K
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0016881Acid-amino acid ligase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04344699670.98226233810.46373414441.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1424585307
GSE13712_SHEARUp0.1119683593
GSE13712_STATICUp0.3587674122
GSE19018Up0.1123583714
GSE19899_A1Up0.1402098701
GSE19899_A2Up0.3879487129
PubMed_21979375_A1Up0.8482745683
PubMed_21979375_A2Up0.5472894647
GSE35957Up0.0454775313
GSE36640Down-0.0982248436
GSE54402Up0.2778296400
GSE9593Down-0.0945674936
GSE43922Up0.4150231417
GSE24585Up0.1669709023
GSE37065Up0.0203814327
GSE28863_A1Up0.2279472394
GSE28863_A2Up0.2321377123
GSE28863_A3Up0.1047657892
GSE28863_A4Up0.0897338768
GSE48662Up0.3808499130

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017347MicroarrayFunctional MTI (Weak)18185580
hsa-miR-877-3pMIMAT0004950MIRT037063CLASHFunctional MTI (Weak)23622248
hsa-miR-744-5pMIMAT0004945MIRT037423CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-1-3pMIMAT0004674MIRT038542CLASHFunctional MTI (Weak)23622248
hsa-miR-505-3pMIMAT0002876MIRT041058CLASHFunctional MTI (Weak)23622248
hsa-miR-328-3pMIMAT0000752MIRT043811CLASHFunctional MTI (Weak)23622248
hsa-miR-93-5pMIMAT0000093MIRT048803CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.