HCSGD entry for SDC4

1. General information

Official gene symbolSDC4
Entrez ID6385
Gene full namesyndecan 4
Other gene symbolsSYND4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0001657Ureteric bud developmentIEAbiological_process
GO:0001968Fibronectin bindingIEAmolecular_function
GO:0005080Protein kinase C bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0005925Focal adhesionIEAcellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006024Glycosaminoglycan biosynthetic processTASbiological_process
GO:0006027Glycosaminoglycan catabolic processTASbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008092Cytoskeletal protein bindingIEAmolecular_function
GO:0008150Biological_processNDbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030204Chondroitin sulfate metabolic processTASbiological_process
GO:0043034CostamereIEAcellular_component
GO:0043202Lysosomal lumenTAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045121Membrane raftIEAcellular_component
GO:0045860Positive regulation of protein kinase activityIEAbiological_process
GO:0051496Positive regulation of stress fiber assemblyIEAbiological_process
GO:0051894Positive regulation of focal adhesion assemblyIEAbiological_process
GO:0070053Thrombospondin receptor activityIMPmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89202804980.01019356790.99999024730.2001470632

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1899669094
GSE13712_SHEARUp0.4325498275
GSE13712_STATICUp0.4040820203
GSE19018Up0.0974259112
GSE19899_A1Down-1.6160995125
GSE19899_A2Down-0.7557975276
PubMed_21979375_A1Down-1.6320586953
PubMed_21979375_A2Down-1.9406348407
GSE35957Down-0.0186598801
GSE36640Down-1.1288854527
GSE54402Down-1.2306173171
GSE9593Up0.2483097683
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.5194336538

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT002795MicroarrayFunctional MTI (Weak)15685193
hsa-miR-1MIMAT0000416MIRT002795Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-124-3pMIMAT0000422MIRT022356MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-1MIMAT0000416NAhsa-miR-115685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.