HCSGD entry for SDC4

1. General information

Official gene symbolSDC4
Entrez ID6385
Gene full namesyndecan 4
Other gene symbolsSYND4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0001657Ureteric bud developmentIEAbiological_process
GO:0001968Fibronectin bindingIEAmolecular_function
GO:0005080Protein kinase C bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0005925Focal adhesionIEAcellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006024Glycosaminoglycan biosynthetic processTASbiological_process
GO:0006027Glycosaminoglycan catabolic processTASbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008092Cytoskeletal protein bindingIEAmolecular_function
GO:0008150Biological_processNDbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030204Chondroitin sulfate metabolic processTASbiological_process
GO:0043034CostamereIEAcellular_component
GO:0043202Lysosomal lumenTAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045121Membrane raftIEAcellular_component
GO:0045860Positive regulation of protein kinase activityIEAbiological_process
GO:0051496Positive regulation of stress fiber assemblyIEAbiological_process
GO:0051894Positive regulation of focal adhesion assemblyIEAbiological_process
GO:0070053Thrombospondin receptor activityIMPmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89202804980.01019356790.99999024730.2001470632

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1899669094
GSE13712_SHEARUp0.4325498275
GSE13712_STATICUp0.4040820203
GSE19018Up0.0974259112
GSE19899_A1Down-1.6160995125
GSE19899_A2Down-0.7557975276
PubMed_21979375_A1Down-1.6320586953
PubMed_21979375_A2Down-1.9406348407
GSE35957Down-0.0186598801
GSE36640Down-1.1288854527
GSE54402Down-1.2306173171
GSE9593Up0.2483097683
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.5194336538

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT002795MicroarrayFunctional MTI (Weak)15685193
hsa-miR-1MIMAT0000416MIRT002795Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-124-3pMIMAT0000422MIRT022356MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-1MIMAT0000416NAhsa-miR-115685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.