HCSGD entry for BHMT

1. General information

Official gene symbolBHMT
Entrez ID635
Gene full namebetaine--homocysteine S-methyltransferase
Other gene symbolsBHMT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000096Sulfur amino acid metabolic processTASbiological_process
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006479Protein methylationNASbiological_process
GO:0006579Amino-acid betaine catabolic processIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008898Homocysteine S-methyltransferase activityIEAmolecular_function
GO:0009086Methionine biosynthetic processIEAbiological_process
GO:0010243Response to organonitrogen compoundIEAbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0047150Betaine-homocysteine S-methyltransferase activityIEA NAS TASmolecular_function
GO:0050666Regulation of homocysteine metabolic processNASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69812206600.84678773980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0187100631
GSE13712_SHEARUp0.0621611365
GSE13712_STATICDown-0.1058322990
GSE19018Up0.0522314260
GSE19899_A1Up0.0752807741
GSE19899_A2Down-0.0287378885
PubMed_21979375_A1Up0.0229257292
PubMed_21979375_A2Up0.1278149537
GSE35957Up0.2464993949
GSE36640Up0.0556231844
GSE54402Up0.0689052916
GSE9593Up0.0615525482
GSE43922Up0.0242141093
GSE24585Down-0.1629461172
GSE37065Down-0.0222490895
GSE28863_A1Down-0.0615665163
GSE28863_A2Down-0.0096042694
GSE28863_A3Up0.0760479663
GSE28863_A4Down-0.0126097830
GSE48662Up0.0348813711

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

S-(D-Carboxybutyl)-L-HomocysteineDB02337 EXPT00843
Citric AcidDB04272 EXPT00922

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.