HCSGD entry for BHMT

1. General information

Official gene symbolBHMT
Entrez ID635
Gene full namebetaine--homocysteine S-methyltransferase
Other gene symbolsBHMT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000096Sulfur amino acid metabolic processTASbiological_process
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006479Protein methylationNASbiological_process
GO:0006579Amino-acid betaine catabolic processIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008898Homocysteine S-methyltransferase activityIEAmolecular_function
GO:0009086Methionine biosynthetic processIEAbiological_process
GO:0010243Response to organonitrogen compoundIEAbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0047150Betaine-homocysteine S-methyltransferase activityIEA NAS TASmolecular_function
GO:0050666Regulation of homocysteine metabolic processNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69812206600.84678773980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0187100631
GSE13712_SHEARUp0.0621611365
GSE13712_STATICDown-0.1058322990
GSE19018Up0.0522314260
GSE19899_A1Up0.0752807741
GSE19899_A2Down-0.0287378885
PubMed_21979375_A1Up0.0229257292
PubMed_21979375_A2Up0.1278149537
GSE35957Up0.2464993949
GSE36640Up0.0556231844
GSE54402Up0.0689052916
GSE9593Up0.0615525482
GSE43922Up0.0242141093
GSE24585Down-0.1629461172
GSE37065Down-0.0222490895
GSE28863_A1Down-0.0615665163
GSE28863_A2Down-0.0096042694
GSE28863_A3Up0.0760479663
GSE28863_A4Down-0.0126097830
GSE48662Up0.0348813711

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

S-(D-Carboxybutyl)-L-HomocysteineDB02337 EXPT00843
Citric AcidDB04272 EXPT00922

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.