HCSGD entry for CCL1


1. General information

Official gene symbolCCL1
Entrez ID6346
Gene full namechemokine (C-C motif) ligand 1
Other gene symbolsI-309 P500 SCYA1 SISe TCA3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005615Extracellular spaceIEAcellular_component
GO:0006874Cellular calcium ion homeostasisTASbiological_process
GO:0006935ChemotaxisTASbiological_process
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008009Chemokine activityIEAmolecular_function
GO:0016032Viral processTASbiological_process
GO:0060326Cell chemotaxisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28975252080.89738342770.98866685251.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0677172303
GSE13712_SHEARDown-0.1406519453
GSE13712_STATICDown-0.0156364600
GSE19018Down-0.0034941422
GSE19899_A1Up0.0544045749
GSE19899_A2Up0.1637058108
PubMed_21979375_A1Up0.0738145310
PubMed_21979375_A2Up0.2571051195
GSE35957Up0.2220808682
GSE36640Down-0.0865837686
GSE54402Up0.0303251160
GSE9593Up0.0430656853
GSE43922Up0.0566413020
GSE24585Down-0.0376709259
GSE37065Up0.2724552404
GSE28863_A1Down-0.1807120633
GSE28863_A2Up0.0334587999
GSE28863_A3Up0.6249308557
GSE28863_A4Up0.1446656905
GSE48662Down-0.0087403844

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-17-5pMIMAT0000070MIRT000257Luciferase reporter assayFunctional MTI19734348
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

25398437In the model studied, this effect is accompanied by proliferation arrest, mitochondrial depolarization, apoptosis, and immune clearance of cancer cells by antitumor leukocytes in a manner reliant upon Ccl5, Ccl1, and Cxcl9
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