HCSGD entry for CCL1
1. General information
| Official gene symbol | CCL1 |
|---|---|
| Entrez ID | 6346 |
| Gene full name | chemokine (C-C motif) ligand 1 |
| Other gene symbols | I-309 P500 SCYA1 SISe TCA3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0006874 | Cellular calcium ion homeostasis | TAS | biological_process |
| GO:0006935 | Chemotaxis | TAS | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008009 | Chemokine activity | IEA | molecular_function |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0060326 | Cell chemotaxis | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2897525208 | 0.8973834277 | 0.9886668525 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0677172303 |
| GSE13712_SHEAR | Down | -0.1406519453 |
| GSE13712_STATIC | Down | -0.0156364600 |
| GSE19018 | Down | -0.0034941422 |
| GSE19899_A1 | Up | 0.0544045749 |
| GSE19899_A2 | Up | 0.1637058108 |
| PubMed_21979375_A1 | Up | 0.0738145310 |
| PubMed_21979375_A2 | Up | 0.2571051195 |
| GSE35957 | Up | 0.2220808682 |
| GSE36640 | Down | -0.0865837686 |
| GSE54402 | Up | 0.0303251160 |
| GSE9593 | Up | 0.0430656853 |
| GSE43922 | Up | 0.0566413020 |
| GSE24585 | Down | -0.0376709259 |
| GSE37065 | Up | 0.2724552404 |
| GSE28863_A1 | Down | -0.1807120633 |
| GSE28863_A2 | Up | 0.0334587999 |
| GSE28863_A3 | Up | 0.6249308557 |
| GSE28863_A4 | Up | 0.1446656905 |
| GSE48662 | Down | -0.0087403844 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-17-5p | MIMAT0000070 | MIRT000257 | Luciferase reporter assay | Functional MTI | 19734348 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25398437 | In the model studied, this effect is accompanied by proliferation arrest, mitochondrial depolarization, apoptosis, and immune clearance of cancer cells by antitumor leukocytes in a manner reliant upon Ccl5, Ccl1, and Cxcl9 |
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