HCSGD entry for SCP2

1. General information

Official gene symbolSCP2
Entrez ID6342
Gene full namesterol carrier protein 2
Other gene symbolsNLTP NSL-TP SCP-2 SCP-CHI SCP-X SCPX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000062Fatty-acyl-CoA bindingIDAmolecular_function
GO:0005102Receptor bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005782Peroxisomal matrixTAScellular_component
GO:0006694Steroid biosynthetic processIDAbiological_process
GO:0006699Bile acid biosynthetic processTASbiological_process
GO:0006701Progesterone biosynthetic processIDAbiological_process
GO:0006869Lipid transportIEAbiological_process
GO:0007031Peroxisome organizationIEAbiological_process
GO:0008206Bile acid metabolic processTASbiological_process
GO:0008526Phosphatidylinositol transporter activityIDAmolecular_function
GO:0015485Cholesterol bindingIDAmolecular_function
GO:0015914Phospholipid transportIDAbiological_process
GO:0016747Transferase activity, transferring acyl groups other than amino-acyl groupsIEAmolecular_function
GO:0032385Positive regulation of intracellular cholesterol transportIDA NASbiological_process
GO:0032934Sterol bindingIEAmolecular_function
GO:0032959Inositol trisphosphate biosynthetic processIDAbiological_process
GO:0033540Fatty acid beta-oxidation using acyl-CoA oxidaseTASbiological_process
GO:0033559Unsaturated fatty acid metabolic processTASbiological_process
GO:0033814Propanoyl-CoA C-acyltransferase activityIEAmolecular_function
GO:0036042Long-chain fatty acyl-CoA bindingIDAmolecular_function
GO:0036109Alpha-linolenic acid metabolic processTASbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0043234Protein complexIDAcellular_component
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045940Positive regulation of steroid metabolic processIDAbiological_process
GO:0070538Oleic acid bindingIDAmolecular_function
GO:0072659Protein localization to plasma membraneIDAbiological_process
GO:1901373Lipid hydroperoxide transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97342981650.01220077880.99999024730.2180154107

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0859986699
GSE13712_SHEARDown-0.3013171180
GSE13712_STATICDown-0.1321421196
GSE19018Down-0.4310405306
GSE19899_A1Down-0.3337944864
GSE19899_A2Down-0.4430998054
PubMed_21979375_A1Down-0.9323330275
PubMed_21979375_A2Down-0.4495876090
GSE35957Up0.2895244935
GSE36640Up0.2340930775
GSE54402Down-0.4067823091
GSE9593Up0.1115624781
GSE43922Down-0.6174010136
GSE24585Up0.0311772363
GSE37065Down-0.2694502262
GSE28863_A1Up0.0520166492
GSE28863_A2Up0.3297991082
GSE28863_A3Down-1.1948410908
GSE28863_A4Down-0.0721659408
GSE48662Down-0.8774740127

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-769-5pMIMAT0003886MIRT016091SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT030161MicroarrayFunctional MTI (Weak)19088304
hsa-miR-1260bMIMAT0015041MIRT052762CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.