HCSGD entry for SCP2

1. General information

Official gene symbolSCP2
Entrez ID6342
Gene full namesterol carrier protein 2
Other gene symbolsNLTP NSL-TP SCP-2 SCP-CHI SCP-X SCPX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000062Fatty-acyl-CoA bindingIDAmolecular_function
GO:0005102Receptor bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005782Peroxisomal matrixTAScellular_component
GO:0006694Steroid biosynthetic processIDAbiological_process
GO:0006699Bile acid biosynthetic processTASbiological_process
GO:0006701Progesterone biosynthetic processIDAbiological_process
GO:0006869Lipid transportIEAbiological_process
GO:0007031Peroxisome organizationIEAbiological_process
GO:0008206Bile acid metabolic processTASbiological_process
GO:0008526Phosphatidylinositol transporter activityIDAmolecular_function
GO:0015485Cholesterol bindingIDAmolecular_function
GO:0015914Phospholipid transportIDAbiological_process
GO:0016747Transferase activity, transferring acyl groups other than amino-acyl groupsIEAmolecular_function
GO:0032385Positive regulation of intracellular cholesterol transportIDA NASbiological_process
GO:0032934Sterol bindingIEAmolecular_function
GO:0032959Inositol trisphosphate biosynthetic processIDAbiological_process
GO:0033540Fatty acid beta-oxidation using acyl-CoA oxidaseTASbiological_process
GO:0033559Unsaturated fatty acid metabolic processTASbiological_process
GO:0033814Propanoyl-CoA C-acyltransferase activityIEAmolecular_function
GO:0036042Long-chain fatty acyl-CoA bindingIDAmolecular_function
GO:0036109Alpha-linolenic acid metabolic processTASbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0043234Protein complexIDAcellular_component
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045940Positive regulation of steroid metabolic processIDAbiological_process
GO:0070538Oleic acid bindingIDAmolecular_function
GO:0072659Protein localization to plasma membraneIDAbiological_process
GO:1901373Lipid hydroperoxide transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97342981650.01220077880.99999024730.2180154107

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0859986699
GSE13712_SHEARDown-0.3013171180
GSE13712_STATICDown-0.1321421196
GSE19018Down-0.4310405306
GSE19899_A1Down-0.3337944864
GSE19899_A2Down-0.4430998054
PubMed_21979375_A1Down-0.9323330275
PubMed_21979375_A2Down-0.4495876090
GSE35957Up0.2895244935
GSE36640Up0.2340930775
GSE54402Down-0.4067823091
GSE9593Up0.1115624781
GSE43922Down-0.6174010136
GSE24585Up0.0311772363
GSE37065Down-0.2694502262
GSE28863_A1Up0.0520166492
GSE28863_A2Up0.3297991082
GSE28863_A3Down-1.1948410908
GSE28863_A4Down-0.0721659408
GSE48662Down-0.8774740127

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-769-5pMIMAT0003886MIRT016091SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT030161MicroarrayFunctional MTI (Weak)19088304
hsa-miR-1260bMIMAT0015041MIRT052762CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.