HCSGD entry for SCNN1B

1. General information

Official gene symbolSCNN1B
Entrez ID6338
Gene full namesodium channel, non-voltage-gated 1, beta subunit
Other gene symbolsBESC1 ENaCb ENaCbeta SCNEB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005272Sodium channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006814Sodium ion transportTASbiological_process
GO:0007588ExcretionTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0015280Ligand-gated sodium channel activityIDA IEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034706Sodium channel complexIDAcellular_component
GO:0035725Sodium ion transmembrane transportIDAbiological_process
GO:0050699WW domain bindingIPImolecular_function
GO:0050891Multicellular organismal water homeostasisIDAbiological_process
GO:0050896Response to stimulusIEAbiological_process
GO:0050909Sensory perception of tasteIEAbiological_process
GO:0055078Sodium ion homeostasisIDAbiological_process
GO:0055085Transmembrane transportTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63929729870.80618721170.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0240631820
GSE13712_SHEARUp0.0170731530
GSE13712_STATICDown-0.1105337641
GSE19018Down-0.0885782389
GSE19899_A1Down-0.0665472341
GSE19899_A2Down-0.0523337725
PubMed_21979375_A1Down-0.0147339927
PubMed_21979375_A2Up0.1598551272
GSE35957Up0.0156544913
GSE36640Up0.1572983956
GSE54402Up0.1175538703
GSE9593Up0.0265142628
GSE43922Up0.0368821235
GSE24585Down-0.0503143411
GSE37065Down-0.0872129077
GSE28863_A1Down-0.0982689182
GSE28863_A2Up0.0754016285
GSE28863_A3Up0.2726769407
GSE28863_A4Up0.2257216073
GSE48662Up0.0429002122

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

TriamtereneDB00384 APRD00079
AmilorideDB00594 APRD00790 | EXPT00514

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.