HCSGD entry for SCNN1B

1. General information

Official gene symbolSCNN1B
Entrez ID6338
Gene full namesodium channel, non-voltage-gated 1, beta subunit
Other gene symbolsBESC1 ENaCb ENaCbeta SCNEB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005272Sodium channel activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006814Sodium ion transportTASbiological_process
GO:0007588ExcretionTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0015280Ligand-gated sodium channel activityIDA IEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034706Sodium channel complexIDAcellular_component
GO:0035725Sodium ion transmembrane transportIDAbiological_process
GO:0050699WW domain bindingIPImolecular_function
GO:0050891Multicellular organismal water homeostasisIDAbiological_process
GO:0050896Response to stimulusIEAbiological_process
GO:0050909Sensory perception of tasteIEAbiological_process
GO:0055078Sodium ion homeostasisIDAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63929729870.80618721170.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0240631820
GSE13712_SHEARUp0.0170731530
GSE13712_STATICDown-0.1105337641
GSE19018Down-0.0885782389
GSE19899_A1Down-0.0665472341
GSE19899_A2Down-0.0523337725
PubMed_21979375_A1Down-0.0147339927
PubMed_21979375_A2Up0.1598551272
GSE35957Up0.0156544913
GSE36640Up0.1572983956
GSE54402Up0.1175538703
GSE9593Up0.0265142628
GSE43922Up0.0368821235
GSE24585Down-0.0503143411
GSE37065Down-0.0872129077
GSE28863_A1Down-0.0982689182
GSE28863_A2Up0.0754016285
GSE28863_A3Up0.2726769407
GSE28863_A4Up0.2257216073
GSE48662Up0.0429002122

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

TriamtereneDB00384 APRD00079
AmilorideDB00594 APRD00790 | EXPT00514

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.