HCSGD entry for SATB1
1. General information
| Official gene symbol | SATB1 |
|---|---|
| Entrez ID | 6304 |
| Gene full name | SATB homeobox 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA IMP | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003690 | Double-stranded DNA binding | TAS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005720 | Nuclear heterochromatin | IEA | cellular_component |
| GO:0006325 | Chromatin organization | TAS | biological_process |
| GO:0006338 | Chromatin remodeling | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006921 | Cellular component disassembly involved in execution phase of apoptosis | TAS | biological_process |
| GO:0008544 | Epidermis development | IEA | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016363 | Nuclear matrix | IEA | cellular_component |
| GO:0016571 | Histone methylation | IEA | biological_process |
| GO:0016605 | PML body | IDA | cellular_component |
| GO:0043367 | CD4-positive, alpha-beta T cell differentiation | IEA | biological_process |
| GO:0043374 | CD8-positive, alpha-beta T cell differentiation | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0050798 | Activated T cell proliferation | IEA | biological_process |
| GO:0060004 | Reflex | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4728924205 | 0.0408078644 | 0.9999902473 | 0.3806179305 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0141066816 |
| GSE13712_SHEAR | Down | -1.4290102044 |
| GSE13712_STATIC | Down | -1.1727025445 |
| GSE19018 | Up | 0.1053370752 |
| GSE19899_A1 | Down | -0.0129159116 |
| GSE19899_A2 | Down | -0.7056335630 |
| PubMed_21979375_A1 | Down | -0.1257958736 |
| PubMed_21979375_A2 | Up | 0.0461663299 |
| GSE35957 | Up | 0.1756328545 |
| GSE36640 | Up | 0.8642211045 |
| GSE54402 | Up | 0.0675335727 |
| GSE9593 | Down | -0.1126770683 |
| GSE43922 | Down | -0.6164109178 |
| GSE24585 | Up | 0.1257188988 |
| GSE37065 | Up | 0.2214477419 |
| GSE28863_A1 | Up | 0.4616944843 |
| GSE28863_A2 | Up | 0.1870354625 |
| GSE28863_A3 | Down | -0.3580107604 |
| GSE28863_A4 | Down | -0.4957468897 |
| GSE48662 | Up | 0.1837574476 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-448 | MIMAT0001532 | MIRT005643 | Immunohistochemistry//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 20798686 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT006722 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22683624 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT006722 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 23542418 |
| hsa-miR-548b-3p | MIMAT0003254 | MIRT016235 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017626 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038509 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
