HCSGD entry for SATB1


1. General information

Official gene symbolSATB1
Entrez ID6304
Gene full nameSATB homeobox 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEA IMPbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003690Double-stranded DNA bindingTASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005720Nuclear heterochromatinIEAcellular_component
GO:0006325Chromatin organizationTASbiological_process
GO:0006338Chromatin remodelingIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006921Cellular component disassembly involved in execution phase of apoptosisTASbiological_process
GO:0008544Epidermis developmentIEAbiological_process
GO:0016032Viral processIEAbiological_process
GO:0016363Nuclear matrixIEAcellular_component
GO:0016571Histone methylationIEAbiological_process
GO:0016605PML bodyIDAcellular_component
GO:0043367CD4-positive, alpha-beta T cell differentiationIEAbiological_process
GO:0043374CD8-positive, alpha-beta T cell differentiationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0050798Activated T cell proliferationIEAbiological_process
GO:0060004ReflexIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47289242050.04080786440.99999024730.3806179305

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0141066816
GSE13712_SHEARDown-1.4290102044
GSE13712_STATICDown-1.1727025445
GSE19018Up0.1053370752
GSE19899_A1Down-0.0129159116
GSE19899_A2Down-0.7056335630
PubMed_21979375_A1Down-0.1257958736
PubMed_21979375_A2Up0.0461663299
GSE35957Up0.1756328545
GSE36640Up0.8642211045
GSE54402Up0.0675335727
GSE9593Down-0.1126770683
GSE43922Down-0.6164109178
GSE24585Up0.1257188988
GSE37065Up0.2214477419
GSE28863_A1Up0.4616944843
GSE28863_A2Up0.1870354625
GSE28863_A3Down-0.3580107604
GSE28863_A4Down-0.4957468897
GSE48662Up0.1837574476

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-448MIMAT0001532MIRT005643Immunohistochemistry//Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI20798686
hsa-miR-191-5pMIMAT0000440MIRT006722Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI22683624
hsa-miR-191-5pMIMAT0000440MIRT006722Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI23542418
hsa-miR-548b-3pMIMAT0003254MIRT016235SequencingFunctional MTI (Weak)20371350
hsa-miR-335-5pMIMAT0000765MIRT017626MicroarrayFunctional MTI (Weak)18185580
hsa-miR-296-3pMIMAT0004679MIRT038509CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.